Understanding Craniofacial Anomalies :The Etiopathogenesis of Craniosynostoses and Facial Clefting
(Hardcover: 583 pages April 2002)
Journal Citations by Authors >
Mark P.Mooney,
>Michael I.Siegel,
Table of Contents: Classification and Terminology
Overview and Introduction
Introduction/
Normal Craniofacial Morphology/
Craniofacial Dysmorphology/
Conclusions/ Terminology and Classification of Craniosynostosis
Introduction/
Historical Perspective/
Conclusions/ Terminology and Classification of Facial Clefting
Introduction
Historical Classifications of Facial Clefts/
Do These Classifications Really Serve a Purpose?/
Back to Semantics/
Is There a Useful System?/
Conclusions/ Embryogenesis and Etiology
Craniofacial Embryogenesis: Normal Developmental Mechanisms/
Introduction/
Early Development/
Neural Crest Tissue/
Craniofacial Development/ Craniofacial Embryogenesis: Abnormal Developmental Mechanisms
Introduction/
Some Relevant Aspects of Craniofacial Evolution and Development/
The Holoprosencephalies and Germ Layer Formation/
Otocephalies/
Syndromes with Major Crest Cell Involvement/
Development Alterations in Facial Clefting with Emphasis on their Multifactorial Etiology/
Abnormal Developmental Mechanisms in the Formation of Tissues and Organs/
Concluding Remarks/ Genetic Etiologies of Craniosynostosis
Introduction/
Genetic Epidemiology of Craniosynostoses/
Phenotypes and Genotypes of Craniosynostoses/
Fibroblast Growth Factor Receptors/
Crouzon Syndrome and FGFR2 Extracellular Domain Mutations/
Apert Syndrome and FGFR2 Ser252Trp and Pro253Arg Mutations/
Pfeiffer Syndrome and FGFR2 Extracellular Mutations and Paralogous Mutations in FGFR1 and FGFR3/
Jackson-Weiss Syndrome and FGFR2 Extracellular Domain Mutations/
Beare-Stevenson Cutis Gyrata Syndrome and FGFR2 Juxta- or Transmembrane Domain Mutations/
Crouzon Syndrome with Acanthosis Nigricans or Crouzonodermoskeletal Syndrome and FGFR3 Ala391Glu Transmembrane Domain Mutation/
FGFR3 Pro250Arg-Associated Coronal Synostosis Syndrome or Muenke Syndrome or Craniosynostosis Adelaide Type/
Pathophysiology of FGFR Mutations in Craniosynostosis/
Saethre Chotzen Syndrome and Robinow-Sorauf Syndrome and TWIST Mutations/
Craniosynostosis, Boston Type, and MSX2 Pro148His Mutation/
Integration of Developmental, Clinical, and Molecular Genetics of Craniosynostoses/ Genetic Etiologies of Facial Clefting
Introduction/
Genetic Etiologies of Syndromic Orofacial Clefts/
Genetic Etiologies of Nonsyndromic Orofacial Clefts/
Environmental Etiologies of Orofacial Clefting and Craniosynostosis/
Introduction/
Nomenclature/
Environmental Etiologies of Orofacial Clefts/
Maternal Factors/
Intrauterine Factors/
Environmental Etiologies of Craniosynostosis/
Summary/ Animal Modeling
Animal Models of Craniosynostosis: Experimental, Congenital, and Transgenic Models/
Introduction: The General Utility of Animal Models for Craniofacial Biology/
Specific Animal Models of Cranial Vault Growth and Craniosynostosis/
Conclusion/ Animal Models of Facial Clefting: Experimental, Congenital, and Transgenic
Introduction/
Midline Craniofacial Development/
Midfacial and Palatal Development/
Primary Palate Development/
Secondary Palate Development/
Transgenic Animal Models for Facial Clefting/
Cranial Vault and Cranial Base Dysmorphology and Growth Disturbances/
Evolutionary Changes in the Cranial Vault and Base: Establishing the Primate Form/
Introduction: Evolutionary Correlates of Human Neuro- and Chondrocranial Morphology/
Phylogenetic Changes in Neuro- and Chondrocranial Morphology/
Phylogenetic Changes in the Nervous System and its Effects on Neuro- and Chondrocranial Morphology/
Skull Base Synchondroses and Comparative Growth/
Conclusions/ Cranial Base Dysmorphology and Growth in the Craniosynostoses
Historical Perspective/
The Etiopathogenesis of Cranial Base Abnormalities/
Cranial Base Growth Patterns in Craniosynostosis/
Conclusions/ Cranial Base Dysmorphology and Growth in Facial Clefting
Introduction/
Prenatal Development of the Cranial Base in Cleft Samples/
Postnatal Development of the Cranial Base in Cleft Samples/
Mechanisms for Basicranial Influences on Clefting/
Conclusions/ Cranial Vault Dysmorphology and Growth in Craniosynostosis
Introduction/
The Relevant Questions/
Soft Tissue-Hard Tissue Interactions as an Explanation for Craniofacial Dysmorphology and Growth/
Formation and Growth of Calvarial Bones and the Cranial Vault/
Lessons from Evolution and Development/
The Genetic Basis of Craniofacial (Dys)Morphology/
Conclusions: Some Preliminary Answers and New Questions/ Midfacial and Mandibular Dysmorphology and Growth Disturbances
Evolutionary Changes in the Midface and Mandible: Establishing the Primate Form/
Introduction/
General Principles of Midfacial Ontogeny/
Anatomic Features of the Primate Midface/
General Principles of Evolutionary Biology/
General Principles of Craniofacial and Midfacial Evolution/
Summary/ Facial Dysmorphology in the Craniosynostoses: Clinical Implications
Introduction/
Theories of Craniosynostosis Etiopathogenesis/
Clinical Management of Craniosynostosis/
Patterns of Dysmorphogenesis/
Experimental Studies/
Conclusions/ Midfacial and Mandibular Dysmorphology and Growth in Facial Clefting: Clinical Implications
Introduction/
Cleft Lip/Cleft Palate/
Other Facial Clefts/
Summary and Conclusions/ Regional Dysmorphology and Growth Disturbances
Dental Development and Anomalies in Craniosynostoses and Facial Clefting/
Introduction/
Tooth Number/
What to Measure and Improving Technologies/
Tooth Crown Formation/
Tooth Size/
Diminished Postnatal Growth with CLP/
Bilateral Asymmetry/
Types of Asymmetry/
Dental Age/
Syndromic Craniosynostoses/
Dental Response to Stress/
CLP: A Developmental Model/
Perspective/ Vocal Tract Anatomy and Functional Consequences in Cleft Lip/Palate and Syndromes of Craniosynostosis
Introduction/
Normal Anatomy of the Vocal Tract/
Congenital Anomalies of the Human Supralaryngeal Vocal Tract/
Summary/
Molecular Biology Studies and Future Directions/
Molecular Studies of Craniosynostosis: Factors Affecting Cranial Suture Morphogenesis and Patency/
Introduction: Regulation of Suture Morphogenesis and Patency/
Molecular Regulation of Suture Morphogenesis and Patency/
Interactions Between Growth and Transcription Factors in Regulating Suture Morphogenesis and Patency/
Conclusions, Future Studies, and Directions/ Molecular Studies of Facial Clefting: From Mouse to Man
Introduction/
Etiology of Nonsyndromic Oral Clefts /
Investigating the Fraser-Juriloff Paradigm/
IGF-IIR/TGF-[beta]2 Epigenetic Network/
Conclusion/
Molecules and Faces: What is on the Horizon?
Introduction/
Molecular Advances in Craniofacial Morphogenesis/
Biomimetics for Repair and Regeneration of Craniofacial Tissues/
Possibilities For Craniofacial and Skeletal Growth Modifications/
Prospectus for the 21st Century/
>Buy from Amazon.com ISBN:047138724X
What Do You Know About Oral Surgery & Anaesthesia (Test Your Knowledge Series)
(Paperback: February 1997)
Understanding Craniofacial Anomalies :The Etiopathogenesis of Craniosynostoses and Facial Clefting
(Hardcover: 583 pages April 2002)