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   Drugs and Chemicals /  B   Benzalkonium Chloride (Drapolene, Germex, Osvan, Zephiran)

A mixture of alkylbenzyldimethylammonium compounds. It is a bactericidal quaternary ammonium detergent used topically in medicaments, deodorants, mouthwashes, as a surgical antiseptic, and as a as preservative and emulsifier in drugs and cosmetics.


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 Pharmacologic Action
  • Detergent
    Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties.
  • Local Anti-Infective Agent
    Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from disinfectants, which are used on inanimate objects.
  • Pharmaceutical Preservative
    Substances added to pharmaceutical preparations to protect them from chemical change or microbial action. They include anti-bacterial agents (Substances that reduce the growth or reproduction of bacteria) and antioxidants (Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues).

 

Topical Antiseptics 25 Jul 2008

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Categorization derived from National Library of Medicine.
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