A phenothiazine that has been used as a hemostatic,
a biological stain, and a dye for wool and silk.
Tolonium chloride has also been used as a diagnostic aid for oral and gastric neoplasms
and in the identification of the parathyroid gland in thyroid surgery.
Williams JA, Pearson GJ, Colles MJ, Wilson M.
The effect of variable energy input from a novel light source on the photoactivated bactericidal action of toluidine blue O on Streptococcus Mutans. (Caries Res. 2003 May-Jun;37(3):190-3.)
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O'Neill JF, Hope CK, Wilson M.
Oral bacteria in multi-species biofilms can be killed by red light in the presence of toluidine blue. (Lasers Surg Med. 2002;31(2):86-90.)
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Exposure of Porphyromonas gingivalis to red light in the presence of the light-activated antimicrobial agent toluidine blue decreases membrane fluidity. (Curr Microbiol. 2002 Aug;45(2):118-22.)
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A study to determine the acceptability in patients and dentists of toluidine blue in screening for oral cancer. (Prim Dent Care. 1999 Apr;6(2):45-50.)
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A study of the uptake of toluidine blue O by Porphyromonas gingivalis and the mechanism of lethal photosensitization. (Photochem Photobiol. 1998 Sep;68(3):370-6.)
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