Migraine
A subtype of vascular headaches characterized by periodic unilateral pulsatile headaches which begin in childhood, adolescence, or early adult life and recur with diminishing frequency during advancing years. The two major subtypes are classic migraine (i.e., migraine with aura) and common migraine (i.e., migraine without aura). Migrainous episodes may be associated with alterations in cerebral blood flow.
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Pharmacologic Action
Opioid Analgesic
Narcotic or opioid substances, synthetic or semisynthetic agents producing profound analgesia, drowsiness, and changes in mood. Mood changes may be pleasurable, therefore creating a potential for the abuse of these agents; the prototype of these is morphine to which all other analgesics are compared.
Narcotic
Originally, agents that caused somnolence or induced sleep; now, any derivative, natural or synthetic, of opium or morphine or any substance that has their effects. Narcotics have potent analgesic effects associated with significant changes in mood and behavior, and with the potential for dependence and tolerance following repeated administration.