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An alkylating agent proposed as an antineoplastic.(ovarian cancer)
It also acts as a chemosterilant for male houseflies and other insects.
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References:
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Pharmacologic Action
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Alkylating Antineoplastic Agent
(A class of drugs that differs from other alkylating agents used clinically in that
they are monofunctional and thus unable to cross-link cellular macromolecules. Among
their common properties are a requirement for metabolic activation to intermediates
with antitumor efficacy and the presence in their chemical structures of N-methyl
groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms
by which each of these drugs acts to kill tumor cells are not completely understood.)
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Ovarian Neoplasms
Tumors or cancer of the ovary. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface epithelium, the stromal endocrine cells, and the totipotent germ cells.
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