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   Drugs and Chemicals /  W   Witch Hazel (Hamamelis)

A plant genus of the family Hamamelidaceae, order Hamamelidales. It is known for the astringent (Agents, usually topical, that cause the contraction of tissues for the control of bleeding or secretions.)
extract of leaves and bark used in over the counter preparations. This should not be confused with the similar named Hamelia genus.




Articles


Antiseptic Effect of a Topical Dermatological Formulation That Contains Hamamelis Distillate and Urea
Formulations of Hamamelis distillate and urea are mainly used for their antiinflammatory, hydrating, and barrier-stabilizing effects in dermatitis maintenance therapy. As bacterial colonization has a central role in the pathogenesis of atopic dermatitis and intertrigo, the antimicrobial activity of such products is considered a welcome, added benefit
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Herbal medicine: from the past to the future
The Food and Drug Administration (FDA) had long insisted that to obtain approval as a drug in this country, herbs had to be supported by the same amount of costly evidence of efficacy required for new synthetic drugs. Because of lack of patentability of the long-known herbs and consequent lack of market exclusivity, companies were unwilling to make the substantial investment required to prove their efficacy. Consequently, only a handful of herbs, many of them quite insignificant from the therapeutic viewpoint – witch hazel (Hamamelis virginiana L.) water, for example – have ever received drug approval in the USA.
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Over the counter ophthalmic preparations
Preparations containing the astringents distilled witch hazel and zinc sulphate are indicated for the relief of minor eye irritations. Astringents are locally acting drugs that precipitate proteins. These preparations are so poorly penetrative that only the cell surface is affected, resulting in greatly reduced cell permeability and thus watering.
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Anti-Inflammatory Effect of Hamamelis Lotion in a UVB Erythema Test
Although Hamamelis virginiana has long been used in the traditional treatment of skin diseases, there are few controlled clinical studies defining the extent of its anti-inflammatory action.
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Book Reviews 05 Jul 2008

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Categorization derived from National Library of Medicine.
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