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   Drugs and Chemicals /  G   Guaifenesin (Humibid, Hytuss, Scott-Tussin)

An expectorant that also has some muscle relaxing action. It is used in many cough preparations.


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   Related Disorders   

Cough
A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
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 Pharmacologic Action
  • Expectorant
    Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here.



Free Full Text 03 Jul 2008
Guaifenesin as a treatment for primary dysmenorrhea
Dysmenorrhea is highly prevalent and causes much work loss and discomfort. A treatment with a new mechanism of action could benefit women of menstruating age. A study was undertaken to assess the efficacy of guaifenesin as a treatment for primary dysmenorrhea because of its effects of cervical dilation and cervical mucous thinning
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Effect of guaifenesin on cough reflex sensitivity
Guaifenesin, a commonly used agent for the treatment of cough, is termed an expectorant since it is believed to alleviate cough discomfort by increasing sputum volume and decreasing its viscosity, thereby promoting effective cough. Despite its common usage, relatively few studies, yielding contrasting results, have been performed to investigate the action and efficacy of guaifenesin.
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Parents on the web: risks for quality management of cough in children
The purpose of this study was to assess the quality of information present on the Internet regarding the home management of cough in children and to examine the applicability of a checklist strategy that would allow consumers to select more trustworthy web pages.
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An in vitro comparison of the mucoactive properties of guaifenesin, iodinated glycerol, surfactant, and albuterol
The mechanism of action of potential mucoactive agents could relate to effects on the mucociliary apparatus or to direct effects on the secretions. The purpose of this study was to determine the in vitro effects of several agents on the properties of mucus simulants and sputum collected from 30 adults with stable chronic bronchitis.
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Over the Counter 03 Jul 2008

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Categorization derived from National Library of Medicine.
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