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Drugs and Chemicals /
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Sildenafil
(Viagra) |
References:
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Pharmacologic Action
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| Free Full Text | 05 Jul 2008 |
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Two Dietary Supplements Contain Undeclared Ingredient
People should not use or purchase two products promoted and offered for sale on Web sites as "dietary supplements" for treating erectile dysfunction and enhancing sexual performance for men. The FDA says that Actra-Rx and Yilishen both contain the active prescription drug ingredient sildenafil, which can be dangerous to people's health, and even life-threatening. Sildenafil is the active ingredient in Viagra, a Pfizer prescription drug product approved in the United States for the treatment of erectile dysfunction. Unlike new drugs, however, dietary supplements don't generally have to go through review by the FDA for safety and effectiveness or be "approved" before they can be marketed, which means that people might not know what's actually contained in these supplements. Read more Effect of sildenafil in cavernous arteries of patients with erectile dysfunction Sildenafil citrate is a type 5 phosphodiesterase inhibitor, which has demonstrated excellent results in the treatment of erectile dysfunction. The effect of sildenafil citrate in the cavernous arteries of patients with erectile dysfunction has not been established yet. The objective of this study was to assess the effect of sildenafil citrate in the cavernous arteries of patients with erectile dysfunction, following an intracavernous injection of alprostadil. Read more The role of the Internet in patient-practitioner relationships: findings from a qualitative research study The study used qualitative interviews and observations of patient-practitioner interaction. Our purposive sample of 47 patients (32 women and 15 men) had all had contact with the health services for information/treatment in relation to hormone replacement therapy (HRT)/menopause and Viagra/erectile dysfunction Read more Erectile dysfunction in kidney transplanted patients: efficacy of sildenafil Erectile dysfunction (ED) is the inability to achieve and/or maintain an erection for satisfactory sexual performance. The effects of kidney transplantation on pre-existing ED are poorly understood, as well as the onset of new ED cases after kidney transplantation. This study aimed to evaluate the effects of kidney transplantation on pre-existing ED, to assess the onset of new ED cases after renal transplantation and to assess both the efficacy and safety of sildenafil. Read more Reasons for discontinuation of sildenafil citrate after successful restoration of erectile function One hundred fifty six patients, whose scores of erectile function domain of the 15-item International Index of Erectile Function (IIEF) increased to 26 or more after sildenafil medication, were included in this study. Six-months after the first sildenafil prescription, compliance to medication and the reason for discontinuity were reviewed by chart or surveyed by telephone. Read more Management of erectile dysfunction: barriers faced by general practitioners GPs' perception of ED being not a serious condition was a major determinant of their prescribing practice. Doctor's age (younger), gender (female), short consultation time and lack of experience were cited as barriers. The GPs' prescribing habits were heavily influenced by the feedback from the first few patients under treatment, the uncertainty of etiology of ED without proper assessment and the profit margin with bulk purchase. Read more Erectile dysfunction: management update Dramatic advances in the management of erectile dysfunction have occurred over the past decade. Oral therapy with vasoactive agents has emerged as first-line treatment and has transformed both the manner in which the public views erectile dysfunction and the way health care providers deliver care. Whereas an extensive investigation was previously common in the management of erectile dysfunction, recent treatment guidelines promote a more minimalist, goal-oriented approach. In this article, we review the physiology of erection, and the pathophysiology, diagnosis and clinical management of erectile dysfunction. We also present the existing evidence for the efficacy of 3 phosphodiesterase inhibitors, the most widely used class of agents for erectile dysfunction. Read more |
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