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Dynastat ®
Generic : Parecoxib Sodium
Active Ingredients :
Parecoxib
Parenterally administered cyclooxygenase-2-selective inhibitor.
Pharmacologic Action :
>Cyclo-oxygenase-2 (COX-2) inhibitor
Compounds or agents that combine with cyclooxygenase (prostaglandin-endoperoxide synthase)
and thereby prevent its substrate-enzyme combination with
arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
- Use in Dentistry :
Postoperative pain associated with surgery.
- Articles :
Cheer SM, Goa KL.
Parecoxib (parecoxib sodium).
(Drugs. 2001;61(8):1133-41; discussion 1142-3.)
>Abstract
Kellstein D, Ott D, Jayawardene S, Fricke J.
Oral valdecoxib and injected parecoxib for acute postoperative pain: a quantitative systematic review
(BMC Anesthesiology 2003, 3:1.)
>Free Full Text
Bayes M, Rabasseda X, Prous JR.
Efficacy and Safety of the First Parenteral Selective Cox-2 Inhibitor, Parecoxib Sodium, in Adult Patients with Postoperative Pain.
(Journal of Indian Medical Association.)
>Free Full Text
Amabile CM, Spencer AP.
Parecoxib for parenteral analgesia in postsurgical patients.
(Ann Pharmacother. 2004 May;38(5):882-6. Epub 2004 Mar 23.)
>Abstract
Mehlisch DR, Desjardins PJ, Daniels S, Hubbard RC.
Single doses of parecoxib sodium intravenously are as effective as ketorolac in reducing pain after oral surgery.
(J Oral Maxillofac Surg. 2003 Sep;61(9):1030-7.)
>Full Text
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