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Arcoxia ®
Generic : Etoricoxib
Active Ingredients :
Etoricoxib
Etoricoxib (Arcoxia) is a novel non steroidal anti-inflammatory drug (NSAID) that selectively inhibits the inducible form of cyclo-oxygenase (COX), COX-2.
Pharmacologic Action :
>Cyclo-oxygenase-2 (COX-2) inhibitor
Compounds or agents that combine with cyclooxygenase (prostaglandin-endoperoxide synthase)
and thereby prevent its substrate-enzyme combination with
arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
- Use in Dentistry :
Postoperative pain associated with surgery.
- Articles :
Malmstrom K, Kotey P, Coughlin H, Desjardins PJ.
A randomized, double-blind, parallel-group study comparing the analgesic effect of etoricoxib to placebo, naproxen sodium, and acetaminophen with codeine using the dental impaction pain model.
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(Clin J Pain. 2004 May-Jun;20(3):147-55.)
>Full Text
Malmstrom K, Sapre A, Couglin H, Agrawal NG, Mazenko RS, Fricke JR Jr.
Etoricoxib in acute pain associated with dental surgery: a randomized, double-blind, placebo- and active comparator-controlled dose-ranging study.
(Clin Ther. 2004 May;26(5):667-79.)
>Full Text
Patrignani P, Capone ML, Tacconelli S.
Clinical pharmacology of etoricoxib: a novel selective COX2 inhibitor.
(Expert Opin Pharmacother. 2003 Feb;4(2):265-84.)
>Full Text
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