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Analgesics







    Prexige ®
    Generic : Lumiracoxib

    Active Ingredients :

    Lumiracoxib
    Cyclo-oxygenase-2 (COX-2) selective inhibitor for the treatment of rheumatoid arthritis, osteoarthritis and acute pain.

    Pharmacologic Action :

    >Cyclo-oxygenase-2 (COX-2) inhibitor

    Compounds or agents that combine with cyclooxygenase (prostaglandin-endoperoxide synthase) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.

  • Use in Dentistry :
    Postoperative pain associated with surgery.

  • Articles :

    Zelenakas K, Fricke JR Jr, Jayawardene S, Kellstein D.

    Analgesic efficacy of single oral doses of lumiracoxib and ibuprofen in patients with postoperative dental pain.
      (Int J Clin Pract. 2004 Mar;58(3):251-6.)
    >Abstract

    Kellstein D, Ott D, Jayawardene S, Fricke J.

    Analgesic efficacy of a single dose of lumiracoxib compared with rofecoxib, celecoxib and placebo in the treatment of post-operative dental pain.
      (Int J Clin Pract. 2004 Mar;58(3):244-50.)
    >Abstract

    Bayes M, Rabasseda X, Prous JR.

    Gateways to clinical trials.
      (Methods Find Exp Clin Pharmacol. 2004 Jun;26(5):357-91.)
    >Abstract




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