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Celebrex ®
Generic : Celecoxib
Active Ingredients :
Celecoxib
A non-steroidal anti-inflammatory agent ,COX-2 selective.
(Compounds or agents that combine with cyclooxygenase-2(prostaglandin-endoperoxide synthase) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes
Inactive Ingredients :
Croscarmellose sodium, gelatin, lactose monohydrate, magnesium stearate, povidone, sodium lauryl sulfate and titanium dioxide.
Pharmacologic Action :
>Non-Steroidal Anti-Inflammatory Agent
>Cyclooxygenase Inhibitor
- Use in Dentistry :
Postoperative pain associated with surgery.
- Articles :
Chen LC, Elliott RA, Ashcroft DM.
Systematic review of the analgesic efficacy and tolerability of COX-2 inhibitors in post-operative pain control.
(J Clin Pharm Ther. 2004 Jun;29(3):215-29.)
>Full Text
Doyle G, Jayawardena S, Ashraf E, Cooper SA.
Efficacy and tolerability of nonprescription ibuprofen versus celecoxib for dental pain.
(J Clin Pharmacol. 2002 Aug;42(8):912-9.)
>Abstract
Malmstrom K, Daniels S, Kotey P, Seidenberg BC, Desjardins PJ.
Comparison of rofecoxib and celecoxib, two cyclooxygenase-2 inhibitors, in postoperative dental pain: a randomized, placebo- and active-comparator-controlled clinical trial.
(Clin Ther. 1999 Oct;21(10):1653-63.)
>Full Text
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