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Atridox ®
Generic : Doxycycline Hyclate
Atridox® is subgingival controlled release drug,composed of two
syringe mixing system.Mixed composition is a yellow viscous liquid
with 10% doxycycline concentration.
Active Ingredients :
>Doxycycline Hyclate
A synthetic
tetracycline derivative with similar antimicrobial activity.
Animal studies suggest that it may cause less tooth staining than other tetracyclines.
Inactive Ingredients :
>Atrigel® delivery system
Pharmacologic Action :
>Antibacterial agent
(ADA approved drug)
- Use in Dentistry :
Atridox is indicated for use in the treatment of chronic adult periodontitis for a gain in clinical attachment,
reduction in probing depth,and reduction in bleeding on probing.
In vitro testing has shown that Porphyromonas gingivalis,Bacteroides forsythus,Prevotella intermedia,Camphylobacter rectus
and Fusobacterium nucleatum which are associated with periodontal disease are
susceptible to doxycycline.
- Porphyromonas gingivalis :
A species of gram-negative, anaerobic, rod-shaped bacteria originally
classified within the bacteroides genus. This bacterium produces a cell-bound,
oxygen-sensitive collagenase and is isolated from the human mouth.
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