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Antibiotics







    Tetracycline

    A naphthacene antibiotic that inhibits Amino Acyl RNA Transfer binding during protein synthesis.

    Pharmacologic Action :

    >Anti-Bacterial Agent

    >Protein Synthesis Inhibitor

  • Use in Dentistry :
    The treatment of orofacial infections (aerobic gram positive cocci and anaerobes),as intracanal medicament in mixtures,local treatment in periodontitis.

  • Articles :

    Rodrigues RM, Goncalves C, Souto R, Feres-Filho EJ, Uzeda M, Colombo AP.

    Antibiotic resistance profile of the subgingival microbiota following systemic or local tetracycline therapy.
      (J Clin Periodontol. 2004 Jun;31(6):420-7.)
    >Full Text

    Mombelli A, Feloutzis A, Bragger U, Lang NP.

    Treatment of peri-implantitis by local delivery of tetracycline. Clinical, microbiological and radiological results.
      (Clin Oral Implants Res. 2001 Aug;12(4):287-94.)
    >Full Text

    Lancaster H, Ready D, Mullany P, Spratt D, Bedi R, Wilson M.

    Prevalence and identification of tetracycline-resistant oral bacteria in children not receiving antibiotic therapy.
      (FEMS Microbiol Lett. 2003 Nov 7;228(1):99-104.)
    >Full Text

    Pavia M, Nobile CG, Angelillo IF.

    Meta-analysis of local tetracycline in treating chronic periodontitis.
      (J Periodontol. 2003 Jun;74(6):916-32.)
    >Abstract

    Smilack JD.

    The tetracyclines.
      (Mayo Clin Proc. 1999 Jul;74(7):727-9.)
    >Abstract




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