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Analgesics







    Percocet ®
    Generic : oxycodone/acetaminophen

    A narcotic analgesic used to treat or prevent moderate to severe pain.

    Active Ingredients :

    Oxycodone
    Semisynthetic derivative of codeine that acts as a narcotic analgesic more potent and addicting than codeine.

    Acetaminophen
    Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.

    Pharmacologic Action :

    >Opioid Analgesic
    >Narcotic

  • Use in Dentistry :
    The treatment of acute pain following oral surgery.

  • Articles :

    Gammaitoni AR, Galer BS, Bulloch S, Lacouture P, Caruso F, Ma T, Schlagheck T.

    Randomized, double-blind, placebo-controlled comparison of the analgesic efficacy of oxycodone 10 mg/acetaminophen 325 mg versus controlled-release oxycodone 20 mg in postsurgical pain.
      (J Clin Pharmacol. 2003 Mar;43(3):296-304.)
    >Free Full Text

    Daniels SE, Desjardins PJ, Talwalker S, Recker DP, Verburg KM.

    The analgesic efficacy of valdecoxib vs. oxycodone/acetaminophen after oral surgery.
      (J Am Dent Assoc. 2002 May;133(5):611-21; quiz 625.)
    >Abstract

    Cooper SA, Precheur H, Rauch D, Rosenheck A, Ladov M, Engel J.

    Evaluation of oxycodone and acetaminophen in treatment of postoperative dental pain.
      (Oral Surg Oral Med Oral Pathol. 1980 Dec;50(6):496-501.)
    >Abstract




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