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In Chinese philosophy and religion, two principles, one negative, dark, and feminine (yin) and one positive, bright, and masculine (yang), from whose interaction all things are produced and all things are dissolved. As a concept the two polar elements referred originally to the shady and sunny sides of a valley or a hill but it developed into the relationship of any contrasting pair: those specified above (female-male, etc.) as well as cold-hot, wet-dry, weak-strong, etc. It is not a distinct system of thought by itself but permeates Chinese life and thought. A balance of yin and yang is essential to health. A deficiency of either principle can manifest as disease. (Encyclopedia Americana)
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References
Exendin-4 induction of Egr-1 expression in INS-1 beta-cells: Interaction of SRF, not YY1, with SRE site of rat Egr-1 promoter. Authors: Kim MJ, Kang JH, Chang SY, Jang HJ, Ryu GR, Ko SH, Jeong IK, Kim MS, Jo YH Journal: J Cell Biochem
Inhibition of Yin Yang 1-Dependent Repressor Activity of DR5 Transcription and Expression by the Novel Proteasome Inhibitor NPI-0052 Contributes to its TRAIL-Enhanced Apoptosis in Cancer Cells. Authors: Baritaki S, Suzuki E, Umezawa K, Spandidos DA, Berenson J, Daniels TR, Penichet ML, Jazirehi AR, Palladino M, Bonavida B Journal: J Immunol
Yin-Yang 1 regulates effector cytokine gene expression and T(H)2 immune responses. Authors: Guo J, Lin X, Williams MA, Hamid Q, Georas SN Journal: J Allergy Clin Immunol
[Research on relationship between angiotensinogen gene M235T and TCM syndrome type in essential hypertension patients] Authors: Wan YX, Zhang TZ Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi
Cancer stem cells: models, mechanisms and implications for improved treatment. Authors: Zhou J, Zhang Y Journal: Cell Cycle
External application of herbal medicine to acupoints. Authors: Yang J, Xu H Journal: J Tradit Chin Med
Loss of p53 induces epidermal growth factor receptor promoter activity in normal human keratinocytes. Authors: Bheda A, Creek KE, Pirisi L Journal: Oncogene
Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor. Authors: Granovsky AE, Rosner MR Journal: Cell Res
Biochemical characterization of Yin Yang 1 - RNA complexes. Authors: Belak ZR, Ficzycz A, Ovsenek N Journal: Biochem Cell Biol
The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Authors: Allavena P, Sica A, Garlanda C, Mantovani A Journal: Immunol Rev
Epidermal growth factor receptors: function modulation by phosphorylation and glycosylation interplay. Authors: Kaleem A, Ahmad I, Hoessli DC, Walker-Nasir E, Saleem M, Shakoori AR, Nasir-Ud-Din Journal: Mol Biol Rep
Deletion of Yin Yang 1 protein in osteosarcoma cells on cell invasion and CXCR4/angiogenesis and metastasis. Authors: de Nigris F, Rossiello R, Schiano C, Arra C, Williams-Ignarro S, Barbieri A, Lanza A, Balestrieri A, Giuliano MT, Ignarro LJ, Napoli C Journal: Cancer Res
Complex mechanism underlying transcriptional control of the haplotyped flavin-containing monooxygenase 3 (FMO3) gene in Japanese: different regulation between mutations in 5'-upstream distal region and common element in proximal region. Authors: Shimizu M, Murayama N, Nagashima S, Fujieda M, Yamazaki H Journal: Drug Metab Pharmacokinet
In silico modulation of HMGN-1 binding to histones and gene expression by interplay of phosphorylation and O-GlcNAc modification. Authors: Ahmad I, Khan TS, Hoessli DC, Walker-Nasir E, Kaleem A, Shakoori AR, Nasir-ud-Din Journal: Protein Pept Lett
The Yin and Yang of anti-Darwinian epigenetics and Darwinian genetics. Authors: Damiani G Journal: Riv Biol
The Yin-Yang of thrombin and activated protein C. Authors: Dutt T, Toh CH Journal: Br J Haematol
[Observation on therapeutic effect of acupuncture on spastic dyskinesia due to stroke] Authors: Hai Y, Yu X Journal: Zhongguo Zhen Jiu
The combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors. Authors: Allouche A, Nolens G, Tancredi A, Delacroix L, Mardaga J, Fridman V, Winkler R, Boniver J, Delvenne P, Begon DY Journal: Breast Cancer Res
Association between trypotphan hydroxylase 2, performance on a continuance performance test and response to methylphenidate in ADHD participants. Authors: Manor I, Laiba E, Eisenberg J, Meidad S, Lerer E, Israel S, Gritsenko I, Tyano S, Faraone SV, Ebstein RP Journal: Am J Med Genet B Neuropsychiatr Genet
Yin-yang activities and vicious cycles in the tumor microenvironment. Authors: Witz IP Journal: Cancer Res
Reconstruction of cheek skin defects by the 'Yin-Yang' rotation of the Mustardé flap and the temporoparietal scalp. Authors: Belmahi A, Oufkir A, Bron T, Ouezzani S Journal: J Plast Reconstr Aesthet Surg
Yin yang 1 directly regulates the transcription of RE-1 silencing transcription factor. Authors: Jiang L, Yao M, Shi J, Shen P, Niu G, Fei J Journal: J Neurosci Res
An investigation into competence in TCM of BSN graduates from technological universities in Taiwan. Authors: Yeh YC, Chung UL Journal: J Nurs Res
Activation-induced cell death signalling in CD4+ T cells by staphylococcal enterotoxin A. Authors: Porichis F, Morou A, Baritaki S, Spandidos DA, Krambovitis E Journal: Toxicol Lett
Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Authors: Broadbent HM, Peden JF, Lorkowski S, Goel A, Ongen H, Green F, Clarke R, Collins R, Franzosi MG, Tognoni G, Seedorf U, Rust S, Eriksson P, Hamsten A, Farrall M, Watkins H, Journal: Hum Mol Genet
Photoreceptor-specific expression, light-dependent localization, and transcriptional targets of the zinc-finger protein Yin Yang 1 in the chicken retina. Authors: Bernard M, Voisin P Journal: J Neurochem
Sphingosine-1-phosphate and endothelin-1 induce the expression of rgs16 protein in cardiac myocytes by transcriptional activation of the rgs16 gene. Authors: Stuebe S, Wieland T, Kraemer E, Stritzky A, Schroeder D, Seekamp S, Vogt A, Chen CK, Patten M Journal: Naunyn Schmiedebergs Arch Pharmacol
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Authors: Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P Journal: Nature
Yin-yang ways of controlling gene expression are now in our hands. Authors: Okamoto H Journal: ACS Chem Biol
A review and integrative analysis of ancient holistic character medicine systems. Authors: Ventegodt S, Thegler S, Andreasen T, Struve F, Jacobsen S, Torp M, Aegedius H, Enevoldsen L, Merrick J Journal: ScientificWorldJournal
Cooperative regulation of p73 promoter by Yin Yang 1 and E2F1. Authors: Wu S, Murai S, Kataoka K, Miyagishi M Journal: Nucleic Acids Symp Ser (Oxf)
Haplotype patterns in cancer-related genes with long-range linkage disequilibrium: no evidence of association with breast cancer or positive selection. Authors: Ribas G, Milne RL, Gonzalez-Neira A, Benítez J Journal: Eur J Hum Genet
Choreographing the end of life in a neonate. Authors: Milstein JM, Raingruber B Journal: Am J Hosp Palliat Care
Yin Yang 1 induces transcriptional activity of p73 through cooperation with E2F1. Authors: Wu S, Murai S, Kataoka K, Miyagishi M Journal: Biochem Biophys Res Commun
'Yin-Yang' functions of transforming growth factor-beta and T regulatory cells in immune regulation. Authors: Wan YY, Flavell RA Journal: Immunol Rev
Immunotoxicity of hydrocortisone on Th1/Th2-related cytokine production is associated with yang-deficient state in traditional Chinese medicine. Authors: Yao C, Wang L, Zhang J, Zhou X, Zhang C Journal: Cell Mol Immunol
Assembly of the Yin Yang 1 transcription factor into messenger ribonucleoprotein particles requires direct RNA binding activity. Authors: Belak ZR, Ovsenek N Journal: J Biol Chem
The CD30 gene promoter microsatellite binds transcription factor Yin Yang 1 (YY1) and shows genetic instability in anaplastic large cell lymphoma. Authors: Franchina M, Woo AJ, Dods J, Karimi M, Ho D, Watanabe T, Spagnolo DV, Abraham LJ Journal: J Pathol
YY1 repressing peroxisome proliferator-activated receptor delta promoter. Authors: He CQ, Ding NZ, Fan W Journal: Mol Cell Biochem
AANA journal course. Update for nurse anesthetists--part 4--life in the balance: the role of serpins in disease genesis and prevention. Authors: Aker J, Biddle C Journal: AANA J
Chinese medicine: a cognitive and epistemological review*. Authors: Kavoussi B Journal: Evid Based Complement Alternat Med
Risk and benefit: the eternal Yin and Yang of thoracic surgery. Authors: Little AG Journal: Thorax
Lysophosphatidylcholine upregulates LOX-1, chemokine receptors, and activation-related transcription factors in human T-cell line Jurkat. Authors: Hara Y, Kusumi Y, Mitsumata M, Li XK, Fujino M Journal: J Thromb Thrombolysis
Empirical dual energy calibration (EDEC) for cone-beam computed tomography. Authors: Stenner P, Berkus T, Kachelriess M Journal: Med Phys
Yin Yang dynamic neurobiological modeling and diagnostic analysis of major depressive and bipolar disorders. Authors: Zhang WR, Pandurangi AK, Peace KE Journal: IEEE Trans Biomed Eng
Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation. Authors: Baritaki S, Katsman A, Chatterjee D, Yeung KC, Spandidos DA, Bonavida B Journal: J Immunol
Cadmium triggers an integrated reprogramming of the metabolism of Synechocystis PCC6803, under the control of the Slr1738 regulator. Authors: Houot L, Floutier M, Marteyn B, Michaut M, Picciocchi A, Legrain P, Aude JC, Cassier-Chauvat C, Chauvat F Journal: BMC Genomics
Identification of regulatory elements in the Cyp19 proximal promoter in rat luteal cells. Authors: Stocco C, Kwintkiewicz J, Cai Z Journal: J Mol Endocrinol
Effect of detoxification, removing stasis and nourishing yin method on corticosteroid-induced hyperlipidemia in patients with systemic lupus erythematosus. Authors: Wen CP, Fan YS, Wang XC, Li XY, Lu KD Journal: Chin J Integr Med
Acupuncture. A fresh look at an ancient practice. Authors: Journal: Mayo Clin Womens Healthsource
The yin and yang of intestinal epithelial cells in controlling dendritic cell function. Authors: Iliev ID, Matteoli G, Rescigno M Journal: J Exp Med
The NO TRAIL to YES TRAIL in cancer therapy (review). Authors: Lee JY, Huerta-Yepez S, Vega M, Baritaki S, Spandidos DA, Bonavida B Journal: Int J Oncol
Molecular cloning and promoter analysis of downregulated in adenoma (DRA). Authors: Alrefai WA, Wen X, Jiang W, Katz JP, Steinbrecher KA, Cohen MB, Williams IR, Dudeja PK, Wu GD Journal: Am J Physiol Gastrointest Liver Physiol
Koro--the psychological disappearance of the penis. Authors: Mattelaer JJ, Jilek W Journal: J Sex Med
YY1 functions with INO80 to activate transcription. Authors: Cai Y, Jin J, Yao T, Gottschalk AJ, Swanson SK, Wu S, Shi Y, Washburn MP, Florens L, Conaway RC, Conaway JW Journal: Nat Struct Mol Biol
[Study on immunological pathogenesis of 59 patients with multiple sclerosis of different TCM syndrome types] Authors: Zhou L, Fan YP, Ye M Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi
Prostaglandin F2alpha suppresses rat steroidogenic acute regulatory protein expression via induction of Yin Yang 1 protein and recruitment of histone deacetylase 1 protein. Authors: Liu Q, Merkler KA, Zhang X, McLean MP Journal: Endocrinology
The yin and yang of education research. Authors: Eva KW Journal: Med Educ
Medicine. The yin-yang of sirtuins. Authors: Dillin A, Kelly JW Journal: Science
The Yin and Yang of COPD: sex/gender differences in the National Emphysema Treatment Trial. Authors: DeMeo DL Journal: Am J Respir Crit Care Med
The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Authors: He Y, Dupree J, Wang J, Sandoval J, Li J, Liu H, Shi Y, Nave KA, Casaccia-Bonnefil P Journal: Neuron
In silico modulation of apoptotic Bcl-2 proteins by mistletoe lectin-1: functional consequences of protein modifications. Authors: Khwaja TA, Wajahat T, Ahmad I, Hoessli DC, Walker-Nasir E, Kaleem A, Qazi WM, Shakoori AR, Din NU Journal: J Cell Biochem
[Treatment of female idiopathic central precocious puberty with Chinese herbal medicine for nourishing yin and purging fire] Authors: Chen XP, Li HL, Zheng YN Journal: Zhongguo Dang Dai Er Ke Za Zhi
Erxian tang--introduction of a Chinese herbal formula, clinical practice, and experimental studies. Authors: Li JJ, Li JT, Fu JP Journal: Chin J Integr Med
Yin Yang-1 inhibits vascular smooth muscle cell growth and intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-cyclin D1 assembly. Authors: Santiago FS, Ishii H, Shafi S, Khurana R, Kanellakis P, Bhindi R, Ramirez MJ, Bobik A, Martin JF, Chesterman CN, Zachary IC, Khachigian LM Journal: Circ Res
Hepatocellular carcinoma-associated gene 2 interacts with MAD2L2. Authors: Li L, Shi Y, Wu H, Wan B, Li P, Zhou L, Shi H, Huo K Journal: Mol Cell Biochem
[Exploration and analysis of theories of five phases, eight trigrams and four elements] Authors: Cao DY Journal: Zhonghua Yi Shi Za Zhi
[The influence of Huang di nei jing (Huangdi's inner classic) on Shuo wen jie zi (the origin of Chinese characters)] Authors: Lan FL Journal: Zhonghua Yi Shi Za Zhi
HLA polymorphisms and genetic markers for traditional Chinese medicine. Authors: Zhou SF Journal: J Altern Complement Med
Rituximab-induced inhibition of antiapoptotic cell survival pathways: implications in chemo/immunoresistance, rituximab unresponsiveness, prognostic and novel therapeutic interventions. Authors: Bonavida B Journal: Oncogene
Yin Yang 1 is a critical regulator of B-cell development. Authors: Liu H, Schmidt-Supprian M, Shi Y, Hobeika E, Barteneva N, Jumaa H, Pelanda R, Reth M, Skok J, Rajewsky K, Shi Y Journal: Genes Dev
Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides. Authors: Yue PY, Mak NK, Cheng YK, Leung KW, Ng TB, Fan DT, Yeung HW, Wong RN Journal: Chin Med
The Yin and Yang of dogs and cats. Authors: Smith SD Journal: Minn Med
Frailty as a dysruption of steroid "syncrinology" in elderly man. Authors: Valenti G Journal: Acta Biomed
[Transient analgesic effect of electroacupuncture at Taiyang (EX-HN 5) for treatment of migraine with hyperactivity of the liver-yang] Authors: Zhou JW, Li J, Li N, Zhang F, Hu LX, Zhao JJ, Zhang Y, Wang CW Journal: Zhongguo Zhen Jiu
Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin Yang 1. Authors: Baritaki S, Huerta-Yepez S, Sakai T, Spandidos DA, Bonavida B Journal: Mol Cancer Ther
Yin and Yang: The Dao of the kidney. Authors: Guo JK Journal: Kidney Int
Yin and yang interplay of IFN-gamma in inflammation and autoimmune disease. Authors: Zhang J Journal: J Clin Invest
Validation of a mathematical model for determining the Yin-Yang nature of fruits. Authors: Ni L, Lin X, Rao P Journal: Asia Pac J Clin Nutr
HLA class II polymorphisms associated with the physiologic characteristics defined by Traditional Chinese Medicine: linking modern genetics with an ancient medicine. Authors: Chen S, Lv F, Gao J, Lin J, Liu Z, Fu Y, Liu Y, Lin B, Xie Y, Ren X, Xu Y, Fan X, Xu A Journal: J Altern Complement Med
PIASy-mediated sumoylation of Yin Yang 1 depends on their interaction but not the RING finger. Authors: Deng Z, Wan M, Sui G Journal: Mol Cell Biol
[Professor Han-jun Tang's experience in treating lymphadenopathy with Yin and Yang theory] Authors: Kui G Journal: Zhong Xi Yi Jie He Xue Bao
TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase. Authors: Xin H, Liu D, Wan M, Safari A, Kim H, Sun W, O'Connor MS, Songyang Z Journal: Nature
The yin and yang of integrative clinical care, education, and research. Authors: Kemper KJ Journal: Explore (NY)
Yin Yang 1 enhances cyclooxygenase-2 gene expression in macrophages. Authors: Joo M, Wright JG, Hu NN, Sadikot RT, Park GY, Blackwell TS, Christman JW Journal: Am J Physiol Lung Cell Mol Physiol
Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry. Authors: Dai J, Jin WH, Sheng QH, Shieh CH, Wu JR, Zeng R Journal: J Proteome Res
Th2 cell-selective enhancement of human IL13 transcription by IL13-1112C>T, a polymorphism associated with allergic inflammation. Authors: Cameron L, Webster RB, Strempel JM, Kiesler P, Kabesch M, Ramachandran H, Yu L, Stern DA, Graves PE, Lohman IC, Wright AL, Halonen M, Klimecki WT, Vercelli D Journal: J Immunol
The role of activating protein 1 in the transcriptional regulation of the human FCGR2B promoter mediated by the -343 G -> C polymorphism associated with systemic lupus erythematosus. Authors: Olferiev M, Masuda E, Tanaka S, Blank MC, Pricop L Journal: J Biol Chem
Haplotype structure of five SNPs within the ACE gene in the Tunisian population. Authors: Rebaï M, Kharrat N, Ayadi I, Rebaï A Journal: Ann Hum Biol
Chitotriosidase: the yin and yang. Authors: Malaguarnera L Journal: Cell Mol Life Sci
Bioethics: a search for moral diversity. Authors: Renzong Q Journal: East Mediterr Health J
Challenges in neuronal apoptosis. Authors: Jellinger KA Journal: Curr Alzheimer Res
Clinical research on nourishing yin and unblocking meridians recipe combined with opioid analgesics in cancer pain management. Authors: Zhang T, Ma SL, Xie GR, Deng QH, Tang ZZ, Pan XC, Zhang M, Xu S Journal: Chin J Integr Med
Yin/Yang polarization: quantitative diagnostic evaluation using biophoton measurement from human hands and feet. Authors: Yang JM, Choi C, Yu JH, Soh KS, Choi SM, Ryu Y Journal: J Altern Complement Med
Yin Yang 1 physically interacts with Hoxa11 and represses Hoxa11-dependent transcription. Authors: Luke MP, Sui G, Liu H, Shi Y Journal: J Biol Chem
[The informatics of human genome and traditional Chinese medicine] Authors: Lin Q, Wang MQ, Wu B, Ding WJ, Li WH, Zhang TE Journal: Yi Chuan
Expression of transcription factor Yin Yang 1 in human osteosarcomas. Authors: de Nigris F, Botti C, de Chiara A, Rossiello R, Apice G, Fazioli F, Fiorito C, Sica V, Napoli C Journal: Eur J Cancer
The role of G-protein-coupled receptor kinase 5 in pathogenesis of sporadic Parkinson's disease. Authors: Arawaka S, Wada M, Goto S, Karube H, Sakamoto M, Ren CH, Koyama S, Nagasawa H, Kimura H, Kawanami T, Kurita K, Tajima K, Daimon M, Baba M, Kido T, Saino S, Goto K, Asao H, Kitanaka C, Takashita E, Hongo S, Nakamura T, Kayama T, Suzuki Y, Kobayashi K, Katagiri T, Kurokawa K, Kurimura M, Toyoshima I, Niizato K, Tsuchiya K, Iwatsubo T, Muramatsu M, Matsumine H, Kato T Journal: J Neurosci
Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Authors: Fu Z, Larson KA, Chitta RK, Parker SA, Turk BE, Lawrence MW, Kaldis P, Galaktionov K, Cohn SM, Shabanowitz J, Hunt DF, Sturgill TW Journal: Mol Cell Biol
Binding of YY1 to the proximal region of the murine beta interferon promoter is essential to allow CBP recruitment and K8H4/K14H3 acetylation on the promoter region after virus infection. Authors: Mokrani H, Sharaf el Dein O, Mansuroglu Z, Bonnefoy E Journal: Mol Cell Biol
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