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sapho syndrome Syndrome consisting of synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis (SAPHO). The most common site of the disease is the upper anterior chest wall, characterized by
predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.


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Additional comments :
(Acquired Hyperostosis Syndrome)


SAPHO syndrome is an acronym for a cluster of clinical manifestations including synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis.


PD Robins, MP Blake, PS Robinson - Clin Nucl Med, 1998


Generally SAPHO syndrome is more common in the paediatric age group, but
it can occur at any stage from childhood to adulthood.


VIMJ Volumes, IMJ Archives


The SAPHO syndrome is observed primarily in children and young adults. The clinical
presentation includes pain, swelling, and tenderness of the affected areas.


P Kopterides, D Pikazis, C Koufos - Arthritis & Rheumatism, 2004



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