preleukemia - Medical Dictionary

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preleukemia		Conditions in which the abnormalities in the peripheral blood or bone marrow represent the early manifestations of acute leukemia, but in which the changes are not of sufficient magnitude or specificity to permit a diagnosis of acute leukemia by the usual clinical criteria. [ Books \| Images \| Discussion groups ]

Additional comments : Articles Myelodysplastic syndromes. Authors: Nimer SD Journal: Blood Genomic instability in myeloid malignancies: Increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair. Authors: Sallmyr A, Fan J, Rassool FV Journal: Cancer Lett Aberrant pre-mRNA splicing of a highly conserved cell cycle regulator, CDC25C, in myelodysplastic syndromes. Authors: Caudill JS, Porcher JC, Steensma DP Journal: Leuk Lymphoma MPL W515L mutation in Chinese patients with myeloproliferative diseases. Authors: Xu W, Li JY, Xia J, Zhang SJ, Fan L, Qiao C Journal: Leuk Lymphoma Prognostic value of circulating CD34(+) cells in myelodysplastic syndromes. Authors: Cesana C, Klersy C, Brando B, Nosari A, Scarpati B, Scampini L, Molteni A, Nador G, Santoleri L, Formenti M, Valentini M, Mazzone A, Morra E, Cairoli R Journal: Leuk Res Mixed-lineage eosinophil/basophil crisis in MDS: a rare form of progression. Authors: Wimazal F, Baumgartner C, Sonneck K, Zauner C, Geissler P, Schur S, Samorapoompichit P, Müllauer L, Födinger M, Agis H, Sperr WR, Valent P Journal: Eur J Clin Invest Epidemiology of Myelodysplastic Syndromes and Chronic Myeloproliferative Disorders in the United States, 2001-2004: Utilizing Data from the NAACCR and SEER Programs. Authors: Rollison DE, Howlader N, Smith MT, Strom SS, Merritt WD, Ries LA, Edwards BK, List AF Journal: Blood Analysis of mitochondrial DNA in 104 patients with myelodysplastic syndromes. Authors: Wulfert M, Küpper AC, Tapprich C, Bottomley SS, Bowen D, Germing U, Haas R, Gattermann N Journal: Exp Hematol Quality of life in myelodysplastic syndromes. A special report from the Myelodysplastic Syndromes Foundation, Inc. Authors: Heptinstall K, Journal: Oncology (Williston Park) Immunophenotype in chronic myelomonocytic leukemia: is it closer to myelodysplastic syndromes or to myeloproliferative disorders? Authors: Subirá D, Font P, Villalón L, Serrano C, Askari E, Góngora E, Castañón S, Gonzalo R, Mata R, Román A, Llamas P Journal: Transl Res Vasculitis and myelodysplasia. Authors: Belizna CC, Kerleau JM, Heron F, Cailleux N, Lévesque H Journal: Isr Med Assoc J DNA instability in low-risk myelodysplastic syndromes: refractory anemia with or without ring sideroblasts. Authors: Novotna B, Neuwirtova R, Siskova M, Bagryantseva Y Journal: Hum Mol Genet [Immuno-suppressive Effects on T Cells Mediated by Mesenchymal Stem Cells from Patients with Myelodysplastic Syndrome.] Authors: Liu LH, Chen H, Chen B, Sun Z, Ye LP, Shi B, Jin JG, Zhao CH Journal: Zhongguo Shi Yan Xue Ye Xue Za Zhi International Working Group on MDS cytogenetics: October 2007 meeting report. Authors: Slovak ML, Dewald GW Journal: Leuk Res Proliferative indices, cytogenetics, immunophenotye and other prognostic parameters in myelodysplastic syndromes. Authors: Varma N, Varma S Journal: Indian J Pathol Microbiol Low erythropoietin production as non-oncogenic co-factor contributing to disease-manifestation in low-risk MDS: A hypothesis supported by unique case reports. Authors: Valent P Journal: Leuk Res Cytogenetic features in myelodysplastic syndromes. Authors: Haase D Journal: Ann Hematol A phase I biological study of MG98, an oligodeoxynucleotide antisense to DNA methyltransferase 1, in patients with high-risk myelodysplasia and acute myeloid leukemia. Authors: Klisovic RB, Stock W, Cataland S, Klisovic MI, Liu S, Blum W, Green M, Odenike O, Godley L, Burgt JV, Van Laar E, Cullen M, Macleod AR, Besterman JM, Reid GK, Byrd JC, Marcucci G Journal: Clin Cancer Res Narrative review: paroxysmal nocturnal hemoglobinuria: the physiology of complement-related hemolytic anemia. Authors: Brodsky RA Journal: Ann Intern Med Diagnostic flow cytometry for low-grade myelodysplastic syndromes. Authors: Ogata K Journal: Hematol Oncol Farnesyltransferase inhibitors and their potential role in therapy for myelodysplastic syndromes and acute myeloid leukaemia. Authors: Braun T, Fenaux P Journal: Br J Haematol Iron overload in myelodysplastic syndromes: A Canadian consensus guideline. Authors: Wells RA, Leber B, Buckstein R, Lipton JH, Hasegawa W, Grewal K, Yee K, Olney HJ, Larratt L, Vickars L, Tinmouth A Journal: Leuk Res Functional analysis of myelodysplastic syndromes-derived mesenchymal stem cells. Authors: Flores-Figueroa E, Montesinos JJ, Flores-Guzmán P, Gutiérrez-Espíndola G, Arana-Trejo RM, Castillo-Medina S, Pérez-Cabrera A, Hernández-Estévez E, Arriaga L, Mayani H Journal: Leuk Res Hemogram and bone marrow morphology in children with chronic aplastic anemia and myelodysplastic syndrome. Authors: Wen JQ, Feng HL, Wang XQ, Pang JP Journal: World J Pediatr Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies. Authors: Jabbour E, Issa JP, Garcia-Manero G, Kantarjian H Journal: Cancer JAK2 V617F patients with essential thrombocythemia present with clinical features of polycythemia vera. Authors: Zhang S, Qiu H, Fischer BS, Li W, Duan L, Sun X, Xu W, Li J Journal: Leuk Lymphoma Current status of epigenetic treatment in myelodysplastic syndromes. Authors: Kuendgen A, Lübbert M Journal: Ann Hematol Susceptibility to Therapy-related Myelodysplastic Syndromes and Acute Myeloid Leukemia. Authors: Sill H Journal: Clin Adv Hematol Oncol Bone marrow glycophorin-positive erythroid cells of myelodysplastic patients responding to high-dose rHuEPO therapy have a different gene expression pattern from those of nonresponders. Authors: Cortelezzi A, Colombo G, Pellegrini C, Silvestris I, Moronetti Mazzeo L, Bosari S, Lambertenghi Deliliers G, Fracchiolla NS Journal: Am J Hematol Acute myeloid leukaemia after treatment with (90)Y-ibritumomab tiuxetan for follicular lymphoma. Authors: Focosi D, Cecconi N, Boni G, Orciuolo E, Galimberti S, Petrini M Journal: Hematol Oncol Assessing donor chimerism using flow cytometry in paroxysmal nocturnal haemoglobinuria after stem cell transplantation--a case report. Authors: Azma RZ, Hamidah NH, Leong CF, Ainoon O, Cheong SK Journal: Malays J Pathol Pregnancy in patients with myelodysplastic syndromes (MDS). Authors: Volpicelli P, Latagliata R, Breccia M, Carmosino I, Stefanizzi C, Napoleone L, Vozella F, Levi A, Natalino F, Alimena G Journal: Leuk Res Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes. Authors: Raj K, Mufti GJ Journal: Ther Clin Risk Manag Erythropoiesis-stimulating agents in the treatment of anemia in myelodysplastic syndromes: a meta-analysis. Authors: Moyo V, Lefebvre P, Duh MS, Yektashenas B, Mundle S Journal: Ann Hematol Chromosome 20 deletions in myelodysplastic syndromes and Philadelphia-chromosome-negative myeloproliferative disorders: characterization by molecular cytogenetics of commonly deleted and retained regions. Authors: Douet-Guilbert N, Basinko A, Morel F, Le Bris MJ, Ugo V, Morice P, Berthou C, De Braekeleer M Journal: Ann Hematol Hematopoietic cell transplantation for patients with myelodysplastic syndromes (MDS): When, how and for whom? Authors: Marcondes M, Deeg HJ Journal: Best Pract Res Clin Haematol Transplantation in remission improves the disease-free survival of patients with advanced myelodysplastic syndromes treated with myeloablative T cell-depleted stem cell transplants from HLA-identical siblings. Authors: Castro-Malaspina H, Jabubowski AA, Papadopoulos EB, Boulad F, Young JW, Kernan NA, Perales MA, Small TN, Hsu K, Chiu M, Heller G, Collins NH, Jhanwar SC, van den Brink M, Nimer SD, O'Reilly RJ Journal: Biol Blood Marrow Transplant Impact of graft cell dose on transplant outcomes following unrelated donor allogeneic peripheral blood stem cell transplantation: higher CD34+ cell doses are associated with decreased relapse rates. Authors: Nakamura R, Auayporn N, Smith DD, Palmer J, Sun JY, Schriber J, Pullarkat V, Parker P, Rodriguez R, Stein A, Rosenthal J, Wang S, Karanas C, Gaal K, Senitzer D, Forman SJ Journal: Biol Blood Marrow Transplant ABO incompatibility is associated with increased non-relapse and GVHD related mortality in patients with malignancies treated with a reduced intensity regimen: a single center experience of 221 patients. Authors: Resnick IB, Tsirigotis PD, Shapira MY, Aker M, Bitan M, Samuel S, Abdul-Hai A, Ackerstein A, Or R, Slavin S Journal: Biol Blood Marrow Transplant Transforming growth factor-beta overexpression in cutaneous extramedullary hematopoiesis of a patient with myelodysplastic syndrome associated with myelofibrosis. Authors: Kawakami T, Kimura S, Kato M, Mizoguchi M, Soma Y Journal: J Am Acad Dermatol [Granulocyte transfusion for the treatment of prolonged pneumonia in a patient with MDS-RAEB-2 at allogeneic hematopoietic stem cell transplantation] Authors: Morita R, Hashino S, Takahashi S, Kanamori H, Onozawa M, Kahata K, Kondo T, Imamura M, Asaka M Journal: Rinsho Ketsueki Role of chromosome 1 pericentric heterochromatin (1q) in pathogenesis of myelodysplastic syndromes: Report of 2 new cases. Authors: Millington K, Hudnall SD, Northup J, Panova N, Velagaleti G Journal: Exp Mol Pathol Miliary tuberculosis with no pulmonary involvement in myelodysplastic syndromes: a curable, yet rarely diagnosed, disease: case report and review of the literature. Authors: Neonakis IK, Alexandrakis MG, Gitti Z, Tsirakis G, Krambovitis E, Spandidos DA Journal: Ann Clin Microbiol Antimicrob Low incidence of secondary neoplasia after autotransplantation for lymphoproliferative disease: the role of pre-transplant therapy. Authors: Laurenti L, Tarnani M, Chiusolo P, La Torre G, Garzia M, Zollino M, Zini G, Balducci M, Leone G, Sica S Journal: Clin Transplant The immunophenotype of different immature, myeloid and B-cell lineage-committed CD34(+) hematopoietic cells allows discrimination between normal/reactive and myelodysplastic syndrome precursors. Authors: Matarraz S, López A, Barrena S, Fernandez C, Jensen E, Flores J, Bárcena P, Rasillo A, Sayagues JM, Sánchez ML, Hernandez-Campo P, Hernandez Rivas JM, Salvador C, Fernandez-Mosteirín N, Giralt M, Perdiguer L, Orfao A Journal: Leukemia Circulating adiponectin and leptin in relation to myelodysplastic syndrome: a case-control study. Authors: Dalamaga M, Nikolaidou A, Karmaniolas K, Hsi A, Chamberland J, Dionyssiou-Asteriou A, Mantzoros CS Journal: Oncology [Myelodysplastic syndrome] Authors: Mitani K Journal: Nippon Rinsho [Paroxysmal nocturnal hemoglobinuria (PNH)] Authors: Nishimura J, Kanakura Y Journal: Nippon Rinsho [Fanconi anemia--genotoxic stress and senescence of hematopoietic stem cells] Authors: Yamashita T, Oda T, Sekimoto T Journal: Nippon Rinsho [Prevalence of anemia in Japan] Authors: Tsujioka T, Tohyama K Journal: Nippon Rinsho [Allogeneic stem cell transplantation for severe aplastic anemia and myelodysplasia] Authors: Okamoto S Journal: Nippon Rinsho [Development trend in new therapeutic approaches for anemia] Authors: Ohyashiki K Journal: Nippon Rinsho [Autoimmune hemolytic anemia] Authors: Karasawa M Journal: Nippon Rinsho [Immune pathophysiology of refractory anemias] Authors: Nakao S Journal: Nippon Rinsho [Overview of the clinical reference guides for the idiopathic hematopoietic disorders] Authors: Omine M Journal: Nippon Rinsho Pyoderma gangrenosum after totally implanted central venous access device insertion. Authors: Inan I, Myers PO, Braun R, Hagen ME, Morel P Journal: World J Surg Oncol Therapy-associated genetic aberrations in patients treated for non-Hodgkin lymphoma. Authors: Basecke J, Podleschny M, Becker A, Seiffert E, Schwiers I, Schwiers R, Haase D, Glass B, Schmitz N, Trumper L, Griesinger F Journal: Br J Haematol Curcumin: From ancient medicine to current clinical trials. Authors: Hatcher H, Planalp R, Cho J, Torti FM, Torti SV Journal: Cell Mol Life Sci Meeting report: myelodysplastic syndromes at ASH 2007. Authors: Itzykson R, Gardin C, Fenaux P Journal: Leukemia New data with arsenic trioxide in leukemias and myelodysplastic syndromes. Authors: Sekeres MA Journal: Clin Lymphoma Myeloma Broad-spectrum antifungal prophylaxis in patients with cancer at high risk for invasive mold infections: point. Authors: Gonzalez AV, Ullmann AJ, Almyroudis NG, Segal BH Journal: J Natl Compr Canc Netw Promoter hypermethylation analysis in myelodysplastic syndromes: Diagnostic & prognostic implication. Authors: Solomon PR, Munirajan AK, Tsuchida N, Muthukumarasamy K, Rathinavel A, Selvam GS, Shanmugam G Journal: Indian J Med Res [Characteristics of cases with chromosome 3q21q26 aberrations.] Authors: Zhang Y, He Q, Shi Y, Dang H, Qiu JY, Huang XJ, Lu DP Journal: Zhongguo Shi Yan Xue Ye Xue Za Zhi [Methylation status of LINE-1 sequences in patients with MDS or secondary AML] Authors: Römermann D, Hasemeier B, Metzig K, Schlegelberger B, Länger F, Kreipe H, Lehmann U Journal: Verh Dtsch Ges Pathol [Molecular diagnosis of chronic myeloproliferative diseases and myelodysplastic syndromes] Authors: Bock O Journal: Verh Dtsch Ges Pathol Time-dependent prognostic scoring system for myelodysplastic syndromes has significant limitations that may influence its reproducibility and practical application. Authors: Bowen DT, Fenaux P, Hellstrom-Lindberg E, de Witte T Journal: J Clin Oncol Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia: molecular classification and treatment options. Authors: Niemeyer CM, Kratz CP Journal: Br J Haematol Granulocyte colony-stimulating factor and interleukin-6 production by myelodysplastic syndrome blasts. Authors: Kobayashi K, Yokote T, Akioka T, Hara S, Hiraoka N, Oka S, Nakayama S, Miyoshi T, Hirata Y, Takubo T, Tsuji M, Hanafusa T Journal: Leuk Lymphoma Phase I clinical study of diphtheria toxin-interleukin 3 fusion protein in patients with acute myeloid leukemia and myelodysplasia. Authors: Frankel A, Liu JS, Rizzieri D, Hogge D Journal: Leuk Lymphoma Iron overload in myelodysplastic syndromes. Authors: Mahesh S, Ginzburg Y, Verma A Journal: Leuk Lymphoma Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Authors: Marcondes AM, Mhyre AJ, Stirewalt DL, Kim SH, Dinarello CA, Deeg HJ Journal: Proc Natl Acad Sci U S A Outcome of patients who develop acute leukemia or myelodysplasia as a second malignancy after solid tumors treated surgically or with strategies that include chemotherapy and/or radiation. Authors: Abdelhameed A, Pond GR, Mitsakakis N, Brandwein J, Chun K, Gupta V, Kamel-Reid S, Lipton JH, Minden MD, Schimmer A, Schuh A, Yee K, Messner HA Journal: Cancer Outcome of patients with myelodysplastic syndromes - experience from a single institution in South Australia. Authors: Hui CH, Horvath N, Lewis I, To LB, Szabo F Journal: Intern Med J The 5q- syndrome. Authors: Giagounidis AA, Aul C Journal: Cancer Treat Res Guidelines on iron chelation therapy in patients with myelodysplastic syndromes and transfusional iron overload. Authors: Gattermann N Journal: Leuk Res Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat: relevance as a marker for daunorubicin sensitivity of leukemia cells. Authors: Sobue S, Nemoto S, Murakami M, Ito H, Kimura A, Gao S, Furuhata A, Takagi A, Kojima T, Nakamura M, Ito Y, Suzuki M, Banno Y, Nozawa Y, Murate T Journal: Int J Hematol Inositide signaling: Nuclear targets and involvement in myelodysplastic syndromes. Authors: Cocco L, Faenza I, Follo MY, Ramazzotti G, Gaboardi GC, Billi AM, Martelli AM, Manzoli L Journal: Adv Enzyme Regul Helicobacter pylori infection might protect from the leukaemic transformation of myelodysplastic syndromes. Authors: Diamantidis MD, Ioannidou-Papagiannaki E, Kountouras J, Mandala E, Klonizakis P, Frida-Michailidou I, Tsapournas G, Haralambidou-Vranitsa S, Klonizakis I Journal: Med Hypotheses [Salt-wasting nephropathy induced by foscarnet treatment for HHV-6 encephalitis in a hematopoietic stem cell transplant] Authors: Najima Y, Ohashi K, Ando M, Koshida A, Yamashita T, Akiyama H, Sakamaki H Journal: Rinsho Ketsueki Disseminated adenovirus disease by multiple adenovirus serotypes following allogeneic hematopoietic stem cell transplantation. Authors: Suzuki HI, Asai T, Okada K, Kazuyama Y, Takahashi T, Kanda Y, Chiba S, Kurokawa M Journal: Biol Blood Marrow Transplant Up-regulation of NK cell activating receptors following allogeneic hematopoietic stem cell transplantation under a lymphodepleting reduced intensity regimen is associated with elevated IL-15 levels. Authors: Boyiadzis M, Memon S, Carson J, Allen K, Szczepanski MJ, Vance BA, Dean R, Bishop MR, Gress RE, Hakim FT Journal: Biol Blood Marrow Transplant Prognostic significance of serial determinations of lactate dehydrogenase (LDH) in the follow-up of patients with myelodysplastic syndromes. Authors: Wimazal F, Sperr WR, Kundi M, Vales A, Fonatsch C, Thalhammer-Scherrer R, Schwarzinger I, Valent P Journal: Ann Oncol An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndrome. Authors: Ebert BL, Galili N, Tamayo P, Bosco J, Mak R, Pretz J, Tanguturi S, Ladd-Acosta C, Stone R, Golub TR, Raza A Journal: PLoS Med Will to live. Authors: Johnson D, Murray JF Journal: New York Rev Books Activation of cytotoxic T-cell receptor gammadelta T lymphocytes in response to specific stimulation in myelodysplastic syndromes. Authors: Kiladjian JJ, Visentin G, Viey E, Chevret S, Eclache V, Stirnemann J, Bourhis JH, Chouaib S, Fenaux P, Caignard A Journal: Haematologica Secondary malignancies after treatment for indolent non-Hodgkin's lymphoma: a 16-year follow-up study. Authors: Sacchi S, Marcheselli L, Bari A, Marcheselli R, Pozzi S, Luminari S, Lombardo M, Buda G, Lazzaro A, Gobbi PG, Stelitano C, Morabito F, Quarta G, Brugiatelli M Journal: Haematologica Practical recommendations on the use of lenalidomide in the management of myelodysplastic syndromes. Authors: Giagounidis A, Fenaux P, Mufti GJ, Muus P, Platzbecker U, Sanz G, Cripe L, Von Lilienfeld-Toal M, Wells RA Journal: Ann Hematol Myeloablative allogeneic bone marrow transplant using T cell depleted allografts followed by post-transplant GM-CSF in high-risk myelodysplastic syndromes. Authors: Warlick ED, O'Donnell PV, Borowitz M, Grupka N, Decloe L, Garrett-Mayer E, Borrello I, Brodsky R, Fuchs E, Huff CA, Luznik L, Matsui W, Ambinder R, Jones RJ, Douglas Smith B Journal: Leuk Res Treatment strategies in myelodysplastic syndromes. Authors: Atallah E, Garcia-Manero G Journal: Cancer Invest Mucormycosis: a rare but serious infection. Authors: Eichna DM, Brown KS, Breen A, Dean RB Journal: Clin J Oncol Nurs Clonality investigation of morphologically dysplastic hematopoietic cells in myelodysplastic syndrome marrows. Authors: Li X, Wu L, Ying S, Chang C, Pu Q Journal: Int J Hematol Dicentric chromosomes and 20q11.2 amplification in MDS/AML with apparent monosomy 20. Authors: Mackinnon RN, Campbell LJ Journal: Cytogenet Genome Res Unusual clonal evolution involving 5q in a case of myelodysplastic syndrome with deletion 5q 31 treated with lenalidomide. Authors: Eclache V, Da Rocha A, Le Roux G, Fenaux P Journal: Haematologica Tolerability, pharmacodynamics, and pharmacokinetics studies of depsipeptide (romidepsin) in patients with acute myelogenous leukemia or advanced myelodysplastic syndromes. Authors: Klimek VM, Fircanis S, Maslak P, Guernah I, Baum M, Wu N, Panageas K, Wright JJ, Pandolfi PP, Nimer SD Journal: Clin Cancer Res Stem cell transplantation in pediatric leukemia and myelodysplasia: state of the art and current challenges. Authors: Bierings M, Nachman JB, Zwaan CM Journal: Curr Stem Cell Res Ther Adjusted dose lenalidomide is safe and effective in patients with deletion (5q) myelodysplastic syndrome and severe renal impairment. Authors: Knop S, Einsele H, Bargou R, Cosgrove D, List A Journal: Leuk Lymphoma Transformation of myelodysplastic syndrome into myeloid/natural killer cell precursor acute leukemia involving mainly lymph nodes. Authors: Kobayashi S, Sato K, Torikai H, Ogura K, Kobayashi A, Bamba Y, Ikeda T, Kimura F, Motoyoshi K Journal: Leuk Lymphoma High prevalence of human T-lymphotropic virus type I carriers among patients with myelodysplastic syndrome refractory anemia with excess of blasts (RAEB), RAEB in transformation and acute promyelocytic leukemia. Authors: Inoue H, Matsushita K, Arima N, Hamada H, Uozumi K, Ozaki A, Akimoto M, Kawada H, Kukita T, Yoshimitsu M, Matsumoto T, Tei C Journal: Leuk Lymphoma [A case-control study of risk factors for myelodysplastic syndromes] Authors: Lv L, Lin GW, Wang XQ, Bao LM, Zou HJ Journal: Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi The value of oral cytarabine ocfosfate and etoposide in the treatment of refractory and elderly AML patients. Authors: Horikoshi A, Takei K, Hosokawa Y, Sawada S Journal: Int J Hematol

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