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gastrinoma A gastrin-secreting neuroendocrine tumor of the non-beta islet cells, the gastrin-secreting cells. This type of tumor is primarily located in the pancreas or the duodenum. Majority of gastrinomas are malignant. They metastasize to the liver; lymph nodes; and bone but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of Zollinger-Ellison syndrome, which sometimes occurs in families with multiple endocrine neoplasia type 1; ( Men 1).


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(Gastrin-Producing Tumor, Ulcerogenic Islet Cell Tumor)



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