dicyclomine - Medical Dictionary

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dicyclomine		A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms. [ Books \| Images \| Discussion groups ]

Additional comments : (Dicycloverin, Bentyl, Bentylol, Di-Cyclonex, Di-Spaz, Dibent, Diclomin, Lomine, Merbentyl, OR-Tyl, Spascol) Articles Blockade of M1 muscarinic acetylcholine receptors modulates the methamphetamine-induced psychomotor stimulant effect. Authors: Lee KW, Tian YH, You IJ, Kwon SH, Ha RR, Lee SY, Kim HC, Jang CG Journal: Neuroscience Mechanisms underlying the antispasmodic and bronchodilatory properties of Terminalia bellerica fruit. Authors: Gilani AH, Khan AU, Ali T, Ajmal S Journal: J Ethnopharmacol Gastrointestinal, selective airways and urinary bladder relaxant effects of Hyoscyamus niger are mediated through dual blockade of muscarinic receptors and Ca2+ channels. Authors: Gilani AH, Khan AU, Raoof M, Ghayur MN, Siddiqui BS, Vohra W, Begum S Journal: Fundam Clin Pharmacol Improving the detection limits of antispasmodic drugs electrodes by using modified membrane sensors with inner solid contact. Authors: Ibrahim H, Issa YM, Abu-Shawish HM Journal: J Pharm Biomed Anal [Drug treatment of irritable bowel syndrome: an unmet need] Authors: Mearin F Journal: Gastroenterol Hepatol Current gut-directed therapies for irritable bowel syndrome. Authors: Chang HY, Kelly EC, Lembo AJ Journal: Curr Treat Options Gastroenterol Clinical inquiries. What is the best treatment for infants with colic? Authors: Crotteau CA, Wright ST, Eglash A Journal: J Fam Pract Role of muscarinic M1 receptors in inhibitory avoidance and contextual fear conditioning. Authors: Soares JC, Fornari RV, Oliveira MG Journal: Neurobiol Learn Mem M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Authors: Caccamo A, Oddo S, Billings LM, Green KN, Martinez-Coria H, Fisher A, LaFerla FM Journal: Neuron Pharmacodynamic effects of darifenacin, a muscarinic M selective receptor antagonist for the treatment of overactive bladder, in healthy volunteers. Authors: Kay GG, Wesnes KA Journal: BJU Int Interaction between M1-muscarinic and glutamatergic NMDA receptors on an inhibitory avoidance task. Authors: Monteiro Moreira K, Lima Ferreira T, Vecchio Fornari R, Perez Figueredo LZ, Menezes Oliveira MG Journal: Brain Res Bull Infantile colic. Authors: Kilgour T, Wade S Journal: Clin Evid Muscarinic M2 and M4 receptors in anterior cingulate cortex: relation to neuropsychiatric symptoms in dementia with Lewy bodies. Authors: Teaktong T, Piggott MA, Mckeith IG, Perry RH, Ballard CG, Perry EK Journal: Behav Brain Res Quantitative determination of pharmaceuticals using nano-electrospray ionization mass spectrometry after reversed phase mini-solid phase extraction. Authors: Qi L, Danielson ND Journal: J Pharm Biomed Anal Potentially inappropriate medication use by elderly persons in U.S. Health Maintenance Organizations, 2000-2001. Authors: Simon SR, Chan KA, Soumerai SB, Wagner AK, Andrade SE, Feldstein AC, Lafata JE, Davis RL, Gurwitz JH Journal: J Am Geriatr Soc Infantile colic. Authors: Kilgour T, Wade S Journal: Clin Evid Experimental analysis of antimicrobial action of dicyclomine hydrochloride. Authors: Karaka P, Kumar KA, Basu LR, Dasgupta A, Ray R, Dastidar SG Journal: Biol Pharm Bull Infantile colic. Authors: Kilgour T, Wade S Journal: Clin Evid Post-marketing surveillance using pharmacy-based cohorts: results of a pilot study. Authors: Louik C, Mitchell AA Journal: Pharmacoepidemiol Drug Saf Chemically modified carbon paste electrode for the potentiometric determination of dicylomine hydrochloride in batch and in FIA conditions. Authors: Ibrahim H, Issa YM, Abu-Shawish HM Journal: Anal Sci Infantile colic. Authors: Kanabar D Journal: J Fam Health Care Dicycloverine for persistent crying in babies: beware recommending dicycloverine treatment in babies. Authors: Steinherz R Journal: BMJ Dicycloverine for persistent crying in babies: dicycloverine is contraindicated in infants. Authors: Goldman MH Journal: BMJ Antibacterial potential of an antispasmodic drug dicyclomine hydrochloride. Authors: Karak P, Kumar KA, Mazumdar K, Mookerjee M, Dastidar SG Journal: Indian J Med Res The effect of fennel (Foeniculum Vulgare) seed oil emulsion in infantile colic: a randomized, placebo-controlled study. Authors: Alexandrovich I, Rakovitskaya O, Kolmo E, Sidorova T, Shushunov S Journal: Altern Ther Health Med Deficits in avoidance responding after paradoxical sleep deprivation are not associated with altered [3H]pirenzepine binding to M1 muscarinic receptors in rat brain. Authors: Moreira KM, Hipólide DC, Nobrega JN, Bueno OF, Tufik S, Oliveira MG Journal: Brain Res Use of pi-acceptors for spectrophotometric determination of dicyclomine hydrochloride. Authors: Bebawy LI, Issa YM, Abdel Moneim KM Journal: J AOAC Int Infantile colic. Authors: Kilgour T, Wade S Journal: Clin Evid Variable effects of previously untested muscarinic receptor antagonists on experimental myopia. Authors: Luft WA, Ming Y, Stell WK Journal: Invest Ophthalmol Vis Sci Infantile colic. Authors: Kilgour T, Wade S Journal: Clin Evid Modulation by adenosine of both muscarinic M1-facilitation and M2-inhibition of [3H]-acetylcholine release from the rat motor nerve terminals. Authors: Oliveira L, Timóteo MA, Correia-de-Sá P Journal: Eur J Neurosci Evidence-based view of safety and effectiveness of pharmacologic therapy for nausea and vomiting of pregnancy (NVP). Authors: Magee LA, Mazzotta P, Koren G Journal: Am J Obstet Gynecol Cimetropium bromide in the treatment of crisis in infantile colic. Authors: Savino F, Brondello C, Cresi F, Oggero R, Silvestro L Journal: J Pediatr Gastroenterol Nutr Evidence based management of nocturnal enuresis. Authors: Evans JH Journal: BMJ Role of 5-HT1A receptors in a mouse passive avoidance paradigm. Authors: Galeotti N, Ghelardini C, Bartolini A Journal: Jpn J Pharmacol Muscarinic receptor subtypes and calcium signaling in Fischer rat thyroid cells. Authors: Jiménez E, Pavía J, Morell V, Martín E, Montiel M Journal: Biochem Pharmacol Irritable Bowel Syndrome. Authors: Wald A Journal: Curr Treat Options Gastroenterol Effects of the selective M1 muscarinic receptor antagonist dicyclomine on emotional memory. Authors: Fornari RV, Moreira KM, Oliveira MG Journal: Learn Mem Muscarinic cholinergic modulation of prepulse inhibition of the acoustic startle reflex. Authors: Jones CK, Shannon HE Journal: J Pharmacol Exp Ther Antispasmodic and anti-diarrhoeal effect of Satureja hortensis L. essential oil. Authors: Hajhashemi V, Sadraei H, Ghannadi AR, Mohseni M Journal: J Ethnopharmacol A risk-benefit assessment of pharmacological and nonpharmacological treatments for nausea and vomiting of pregnancy. Authors: Mazzotta P, Magee LA Journal: Drugs Dicyclomine, an M1 muscarinic antagonist, reduces infarct volume in a rat subdural hematoma model. Authors: Jiang ZW, Gong QZ, Di X, Zhu J, Lyeth BG Journal: Brain Res Antinociceptive effect of R-(+)-hyoscyamine on the conjunctival reflex test in rabbits. Authors: Ghelardini C, Galeotti N, Fantetti L, Gualtieri F, Scapecchi S, Bartolini A Journal: Jpn J Pharmacol Binding profiles of a series of 2-arylpropionic acid esters on cloned human muscarinic receptor subtypes (m1-m5) and their relationship to nootropic activity. Authors: Ghelardini C, Mizuma I, Gualtieri F, Bartolini A, Galeotti N, Romanelli MN, Teodori E Journal: Arzneimittelforschung Treatment of urge incontinence in Veterans Affairs medical centers. Authors: Malone DC, Okano GJ Journal: Clin Ther Dose effect of dicyclomine on the reduction of peristaltic artifacts on MRI of the abdomen. Authors: Martí-Bonmatí L, Dosdá R, Ronchera-Oms CL, Casillas C Journal: Abdom Imaging Presynaptic muscarinic (M3) receptors reduce excitatory transmission in dopamine neurons of the rat mesencephalon. Authors: Grillner P, Bonci A, Svensson TH, Bernardi G, Mercuri NB Journal: Neuroscience Reversal of prolonged unconsciousness by naloxone after an intravascular injection of a local anesthetic and clonidine. Authors: Botero M, Enneking FK Journal: Anesth Analg Nausea during pregnancy and congenital heart defects: a population-based case-control study. Authors: Boneva RS, Moore CA, Botto L, Wong LY, Erickson JD Journal: Am J Epidemiol Different effects of an oral anticholinergic drug on gastroesophageal reflux in upright and supine position in normal, ambulant subjects: a pilot study. Authors: Koerselman J, Pursnani KG, Peghini P, Mohiuddin MA, Katzka D, Akkermans LM, Castell DO Journal: Am J Gastroenterol Role of 5-HT4 receptors in the mouse passive avoidance test. Authors: Galeotti N, Ghelardini C, Bartolini A Journal: J Pharmacol Exp Ther Effectiveness of treatments for infantile colic: systematic review. Authors: Lucassen PL, Assendelft WJ, Gubbels JW, van Eijk JT, van Geldrop WJ, Neven AK Journal: BMJ Antinociceptive and antiamnesic properties of the presynaptic cholinergic amplifier PG-9. Authors: Ghelardini C, Galeotti N, Gualtieri F, Marchese V, Bellucci C, Bartolini A Journal: J Pharmacol Exp Ther Antenatal therapeutic drug exposure and fetal/neonatal tumours: review of 89 cases. Authors: Satgé D, Sasco AJ, Little J Journal: Paediatr Perinat Epidemiol Properties of carbachol-induced oscillatory activity in rat hippocampus. Authors: Williams JH, Kauer JA Journal: J Neurophysiol Antiamnesic activity of metoclopramide, cisapride and SR-17 in the mouse passive avoidance test. Authors: Galeotti N, Ghelardini C, Teodori E, Gualtieri F, Bartolini A Journal: Pharmacol Res Cyclohexylamine additives for enhanced peptide separations in reversed phase liquid chromatography. Authors: Cole SR, Dorsey JG Journal: Biomed Chromatogr Stereoselective increase in cholinergic transmission by R-(+)-hyoscyamine. Authors: Ghelardini C, Gualtieri F, Novella Romanelli M, Angeli P, Pepeu G, Grazia Giovannini M, Casamenti F, Malmberg-Aiello P, Giotti A, Bartolini A Journal: Neuropharmacology Pharmacological characterization and distribution of muscarinic receptors in human placental syncytiotrophoblast brush-border and basal plasma membranes. Authors: Pavía J, Muñoz M, Jiménez E, Martos F, Gonzalez-Correa JA, De la Cruz JP, Garcia V, Sanchez de la Cuesta F Journal: Eur J Pharmacol Antinociception induced by SM 32 depends on a central cholinergic mechanism. Authors: Ghelardini C, Galeotti N, Gualtieri F, Novella Romanelli M, Bartolini A Journal: Pharmacol Res [Management of infantile colics] Authors: Savino F, Oggero R Journal: Minerva Pediatr Reduction of peristaltic artifacts on magnetic resonance imaging of the abdomen: a comparative evaluation of three drugs. Authors: Martí-Bonmatí L, Graells M, Ronchera-Oms CL Journal: Abdom Imaging Infantile colic: natural history and treatment. Authors: Lehtonen LA, Rautava PT Journal: Curr Probl Pediatr Reduced flexibility analogs of analgesic and cognition enhancing alpha-tropanyl esters. Authors: Manetti D, Romanelli MN, Bartolini A, Dei S, Ghelardini C, Gualtieri F, Matucci R, Scapecchi S, Teodori E Journal: Arch Pharm (Weinheim) Synthesis and enantioselectivity of the enantiomers of PG9 and SM21, new potent analgesic and cognition-enhancing drugs. Authors: Romanelli MN, Bartolini A, Bertucci C, Dei S, Ghelardini C, Giovannini MG, Gualtieri F, Pepeu G, Scapecchi S, Teodori E Journal: Chirality [Information about adverse effects of drugs is not included in Fass (Swedish drug catalog)] Authors: Jacks B Journal: Lakartidningen The relation of gastroesophageal reflux disease and its treatment to adenocarcinomas of the esophagus and gastric cardia. Authors: Chow WH, Finkle WD, McLaughlin JK, Frankl H, Ziel HK, Fraumeni JF Journal: JAMA Classification of the presynaptic muscarinic receptor subtype that regulates 3H-acetylcholine secretion in the guinea pig urinary bladder in vitro. Authors: Alberts P Journal: J Pharmacol Exp Ther Microbore liquid chromatography of tertiary amine anticholinergic pharmaceuticals with tris(2,2'-bipyridine)ruthenium(III) chemiluminescence detection. Authors: Holeman JA, Danielson ND Journal: J Chromatogr Sci Prejunctional muscarinic receptors regulating neurotransmitter release in airways. Authors: Kilbinger H, von Bardeleben RS, Siefken H, Wolf D Journal: Life Sci Pre-clinical and clinical pharmacology of selective muscarinic M3 receptor antagonists. Authors: Wallis RM Journal: Life Sci M3 muscarinic receptors on murine HSDM1C1 cells: further functional, regulatory, and receptor binding studies. Authors: Sharif NA, To ZP, Wong KH, Delmendo RE, Whiting RL, Eglen RM Journal: Neurochem Res Bendectin and birth defects: I. A meta-analysis of the epidemiologic studies. Authors: McKeigue PM, Lamm SH, Linn S, Kutcher JS Journal: Teratology Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 2. 2-Phenoxy-, 2-(phenylthio)-, and 2-(phenylamino)alkanoic acid esters. Authors: Gualtieri F, Bottalico C, Calandrella A, Dei S, Giovannoni MP, Mealli S, Romanelli MN, Scapecchi S, Teodori E, Galeotti N Journal: J Med Chem Involvement of muscarinic M2 and M3, but not of M1 and M4 receptors in vagally stimulated contractions of rabbit bronchus/trachea. Authors: Eltze M, Galvan M Journal: Pulm Pharmacol Dietary modifications versus dicyclomine hydrochloride in the treatment of severe infantile colics. Authors: Oggero R, Garbo G, Savino F, Mostert M Journal: Acta Paediatr Efficacy of injectable anticholinergic drugs against soman-induced convulsive/subconvulsive activity. Authors: Anderson DR, Harris LW, Bowersox SL, Lennox WJ, Anders JC Journal: Drug Chem Toxicol Characterization of muscarinic receptors in guinea-pig uterus. Authors: Doods HN, Willim KD, Boddeke HW, Entzeroth M Journal: Eur J Pharmacol Study of prescription drugs in the first trimester and congenital malformations. Authors: McBride WG Journal: Aust N Z J Obstet Gynaecol Preliminary note: dangerous use of anticholinergic drugs in Brazil. Authors: Carlini EA Journal: Drug Alcohol Depend Muscarinic M3 receptors mediate total inositol phosphates accumulation in murine HSDM1C1 fibrosarcoma cells. Authors: Eglen RM, Sharif NA, To ZP Journal: Eur J Pharmacol Muscarinic receptor subtypes in bovine adrenal medulla. Authors: Aguilar JS, Ballesta JJ, Reig JA, Palmero M, Viniegra S, Criado M Journal: Neurochem Res Dicyclomine for medical management of persistent anal fissure with associated spasm of the internal sphincter. Authors: Miller LG, Rogers JC, Brown EB, Perkins G Journal: Tex Med Drug consumption during the first 18 months of life of infants from smoking and non-smoking families. Authors: Håkansson A, Petersson C Journal: Br J Gen Pract Chronic nonspecific diarrhea of childhood. Authors: Treem WR Journal: Clin Pediatr (Phila) Activation of T84 cell chloride channels by carbachol involves a phosphoinositide-coupled muscarinic M3 receptor. Authors: Dickinson KE, Frizzell RA, Sekar MC Journal: Eur J Pharmacol Prejunctional muscarine receptors in the rabbit ear artery differ from M1, M2 and M3 muscarine receptors. Authors: Darroch SA, Choo LK, Mitchelson F Journal: Naunyn Schmiedebergs Arch Pharmacol Pharmacological evaluation of JO 1870: relation to the potential treatment of urinary bladder incontinence. Authors: Soulard C, Pascaud X, Roman FJ, Grouhel A, Junien JL Journal: J Pharmacol Exp Ther Role of muscarinic receptor subtypes in central antinociception. Authors: Bartolini A, Ghelardini C, Fantetti L, Malcangio M, Malmberg-Aiello P, Giotti A Journal: Br J Pharmacol Use of prescription drugs in the first trimester and congenital malformations. Authors: Correy JF, Newman NM, Collins JA, Burrows EA, Burrows RF, Curran JT Journal: Aust N Z J Obstet Gynaecol Muscarinic stimulation of adenylate cyclase activity of rat olfactory bulb. II. Characterization of the antagonist sensitivity and comparison with muscarinic inhibitions of the enzyme in striatum and heart. Authors: Olianas MC, Onali P Journal: J Pharmacol Exp Ther Is field (vagal) stimulation of gastric acid secretion mediated by M1 or non-M1 muscarinic receptors? A methodical problem exemplified in the mouse stomach in vitro. Authors: Kromer W, Eltze M Journal: J Auton Pharmacol Characterization of muscarinic receptors mediating endothelium-dependent relaxation of bovine coronary artery. Authors: Brunner F, Kühberger E, Groschner K, Pöch G, Kukovetz WR Journal: Eur J Pharmacol Heterogeneity of muscarinic receptor subtypes in cerebral blood vessels. Authors: Garcia-Villalon AL, Krause DN, Ehlert FJ, Duckles SP Journal: J Pharmacol Exp Ther Noncardiac chest pain in adolescents and children with mitral valve prolapse. Authors: Woolf PK, Gewitz MH, Berezin S, Medow MS, Stewart JM, Fish BG, Glassman MS, Newman LJ Journal: J Adolesc Health Evidence for facilitatory and inhibitory muscarinic receptors on postganglionic sympathetic nerves in mouse isolated atria. Authors: Cost M, Majewski H Journal: Br J Pharmacol M1 muscarinic antagonists interact with sigma recognition sites. Authors: Hudkins RL, DeHaven-Hudkins DL Journal: Life Sci Investigation into atropine-induced antinociception. Authors: Ghelardini C, Malmberg-Aiello P, Giotti A, Malcangio M, Bartolini A Journal: Br J Pharmacol Muscarinic receptors mediating inhibition of gamma-aminobutyric acid release in rat corpus striatum and their pharmacological characterization. Authors: Raiteri M, Marchi M, Paudice P, Pittaluga A Journal: J Pharmacol Exp Ther Characterization of a muscarinic receptor controlling Cl- secretion in hen trachea. Authors: Winding B, Bindslev N Journal: Am J Physiol

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