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dactinomycin		A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015) [ Articles | Books | Images | Discussion groups ]
Additional comments : (Actinomycin, Actinomycin D, Meractinomycin, Ac-De, Cosmegen, Cosmegen Lyovac)

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