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cystic fibrosis An autosomal recessive genetic disease of the exocrine glands.
It is caused by mutations in the gene encoding the cystic fibrosis
transmembrane conductance regulator expressed in several organs including the lung,the pancreas, the biliary system, and the sweat glands. Cystic fibrosis is characterized
by epithelial secretory dysfunction associated with ductal obstruction resulting in airway obstruction;chronic respiratory infections; pancreatic insufficiency; maldigestion; salt depletion; and heat prostration.


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(Mucoviscidosis, Fibrocystic Disease of Pancreas)



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