captopril - Medical Dictionary

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captopril		A potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the renin-angiotensin system and inhibits pressure responses to exogenous angiotensin. [ Articles \| Books \| Images \| Discussion groups ]

Additional comments : (Capoten, Lopirin) Articles Racial analysis of patients with myocardial infarction complicated by heart failure and/or left ventricular dysfunction treated with valsartan, captopril, or both. Authors: Prisant LM, Thomas KL, Lewis EF, Huang Z, Francis GS, Weaver WD, Pfeffer MA, McMurray JJ, Califf RM, Velazquez EJ Journal: J Am Coll Cardiol Prevention of type 2 diabetes mellitus with angiotensin-converting-enzyme inhibitors. Authors: Solski LV, Longyhore DS Journal: Am J Health Syst Pharm Eph receptors and zonation in the rat adrenal cortex. Authors: Vinson G, Brennan C, Chittka A, Barker S Journal: J Endocrinol Preparation of a Matrix Type Multiple-Unit Gastro Retentive Floating Drug Delivery System for Captopril Based on Gas Formation Technique: In Vitro Evaluation. Authors: Meka L, Kesavan B, Chinnala KM, Vobalaboina V, Yamsani MR Journal: AAPS PharmSciTech B(2) kinin receptor activation is the predominant mechanism by which trypsin mediates endothelium-dependent relaxation in bovine coronary arteries. Authors: Drummond GR, Selemidis S, Cocks TM Journal: Naunyn Schmiedebergs Arch Pharmacol Effect of different angiotensin-converting-enzyme inhibitors on mortality among elderly patients with congestive heart failure. Authors: Pilote L, Abrahamowicz M, Eisenberg M, Humphries K, Behlouli H, Tu JV Journal: CMAJ RAS blockade with ARB and ACE inhibitors: current perspective on rationale and patient selection. Authors: Werner C, Baumhäkel M, Teo KK, Schmieder R, Mann J, Unger T, Yusuf S, Böhm M Journal: Clin Res Cardiol Captopril Normalizes Insulin Signaling and Insulin-Regulated Substrate Metabolism in Obese (ob/ob) Mouse Hearts. Authors: Tabbi-Anneni I, Buchanan J, Cooksey RC, Abel ED Journal: Endocrinology Body Mass Index Predicts Plasma Aldosterone Concentrations in Overweight-Obese Primary Hypertensive Patients. Authors: Rossi GP, Belfiore A, Bernini G, Fabris B, Caridi G, Ferri C, Giacchetti G, Letizia C, Maccario M, Mannelli M, Palumbo G, Patalano A, Rizzoni D, Rossi E, Pessina AC, Mantero F, Journal: J Clin Endocrinol Metab Comparison of effects of combined ACE inhibitor and low-dose thiazide diuretic with ACE inhibitor alone on insulin action in patients with hypertension and Type 2 diabetes: a double-blind crossover study. Authors: McLaughlin DM, Atkinson AB, Ennis CN, Browne J, Hunter SJ, Sheridan B, Bell PM Journal: Diabet Med [A comparaison of the effect of the oral captopril and nicardipine in hypertensive crisis] Authors: Addad F, Ferjani H, Chaabani A, Jelliti M, Gamra H, Makni H, Khaldoun BH, Dridi Z, Ben Farhat M Journal: Tunis Med Oestrogenic influence on brain AT1 receptor signalling on the thirst and salt appetite in osmotically-stimulated and sodium-depleted female rats. Authors: Mecawi AS, Lepletier A, Fonseca FV, Araujo IG, Reis LC Journal: Exp Physiol The Effect of Pentoxifylline on Proteinuria in Diabetic Kidney Disease: A Meta-analysis. Authors: McCormick BB, Sydor A, Akbari A, Fergusson D, Doucette S, Knoll G Journal: Am J Kidney Dis Beta-blocker and angiotensin-converting enzyme inhibitor may limit certain cardiac adverse effects of clozapine. Authors: Rostagno C, Di Norscia G, Placidi GF, Gensini GF Journal: Gen Hosp Psychiatry Oral vasodilators for primary Raynaud's phenomenon. Authors: Vinjar B, Stewart M Journal: Cochrane Database Syst Rev [Clinical trials of ACE inhibitors and ARB for treatment of patients with hypertension, heart failure, and diabetic nephropathy in Japan--special reference to the dosage schedule and adverse effects] Authors: Kageyama S Journal: Nippon Yakurigaku Zasshi [Effect of compound qidan liquid on early ventricular remodeling after acute myocardial infarction in Chinese mini-pigs] Authors: Shi DZ, Ma LB, Liu JG, et al Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi Gene Expression Profiles of Vascular Smooth Muscle Show Differential Expression of Mitogen-Activated Protein Kinase Pathways during Captopril Therapy of Heart Failure. Authors: Chen FC, Brozovich FV Journal: J Vasc Res Contractility of Placental Vascular Smooth Muscle Cells in Response to Stimuli Produced by the Placenta: Roles of ACE vs. Non-ACE and AT1 vs. AT2 in Placental Vessel Cells. Authors: Benoit C, Gu Y, Zhang Y, Alexander JS, Wang Y Journal: Placenta [Comparative study of Scrophulariae and Aconite in inhibiting myocardial hypertrophy in rats and mice.] Authors: Gu WL, Chen CX, Wang Y Journal: Zhong Xi Yi Jie He Xue Bao Anti-hypertensive effects of the methanol/methylene chloride stem bark extract of Mammea africana in l-NAME-induced hypertensive rats. Authors: Nguelefack-Mbuyo PE, Nguelefack TB, Dongmo AB, Afkir S, Azebaze AG, Dimo T, Legssyer A, Kamanyi A, Ziyyat A Journal: J Ethnopharmacol Accurate aqueous proton dissociation constants calculations for selected Angiotensin-converting enzyme inhibitors. Authors: Sramko M, Smiesko M, Remko M Journal: J Biomol Struct Dyn In vivo effect of ACE inhibiting in mealworms on ovarian composition and ecdysteroid amounts. Authors: Soltani-Mazouni N, Bouteldja D, Lemeire E, Smagghe G Journal: Commun Agric Appl Biol Sci The in vivo effects of Tulbhagia violacea on blood pressure in a salt-sensitive rat model. Authors: Mackraj I, Ramesar S, Singh M, Govender T, Baijnath H, Singh R, Gathiram P Journal: J Ethnopharmacol Calcium-independent and 1,25(OH)(2)D(3)-dependent regulation of the renin-angiotensin system in 1alpha-hydroxylase knockout mice. Authors: Zhou CL, Lu FX, Cao KX, Xu D, Goltzman D, Miao DS Journal: Kidney Int Step nonisothermal method in kinetics studies of captopril oxidation under compressed oxygen. Authors: Lin B, Zhan XC, Li LL, Li CR, Qi HJ, Tao JL Journal: Yakugaku Zasshi Blood pressure lowering effects of niacin-bound chromium(III) (NBC) in sucrose-fed rats: Renin-angiotensin system. Authors: Perricone NV, Bagchi D, Echard B, Preuss HG Journal: J Inorg Biochem [New approaches to the drug prophylaxis of mammary tumor: evaluation of the prophylactic effect of lovastatin and captopril in rats with experimental mammary gland tumors] Authors: Chochieva AR, Bolieva LZ, Dzhioev FK Journal: Eksp Klin Farmakol A case of hyperreninemic hypertension with bilateral positive captopril renography but without renovascular stenosis. Authors: Okura T, Irita J, Enomoto D, Manabe S, Kurata M, Miyoshi K, Fukuoka T, Higaki J Journal: Hypertens Res Effects of antihypertensive drugs on alcohol-induced functional responses of cultured human endothelial cells. Authors: Soardo G, Donnini D, Moretti M, Milocco C, Catena C, Sechi LA Journal: Hypertens Res Long-term plasma levels and dose modulation of alacepril in patients with chronic renal failure. Authors: Nonoguchi H, Kiyama S, Kitamura K, Naruse M, Tomita M, Tazoe N, Tajiri M, Nakayama Y, Kohda Y, Inoue T, Tomita K Journal: Hypertens Res Comparison of renal function and cardiovascular risk following acute myocardial infarction in patients with and without diabetes mellitus. Authors: Anavekar NS, Solomon SD, McMurray JJ, Maggioni A, Rouleau JL, Califf R, White H, Kober L, Velazquez E, Pfeffer MA Journal: Am J Cardiol The Antihypertensive Effects of Quercetin in a Salt-sensitive Model of Hypertension. Authors: Mackraj I, Govender T, Ramesar S Journal: J Cardiovasc Pharmacol Degradation kinetics of methionine5-enkephalin by select brain areas from patients with chronic schizophrenia. Authors: Mosnaim AD, Nguyen TD, Puente J, Wolf ME Journal: Am J Ther Inhibition of opioid release in the rat spinal cord by alpha(2C) adrenergic receptors. Authors: Chen W, Song B, Marvizón JC Journal: Neuropharmacology Protective effects of ACE inhibitors on vascular endothelial dysfunction induced by exogenous advanced oxidation protein products in rats. Authors: Chen SX, Song T, Zhou SH, Liu YH, Wu SJ, Liu LY Journal: Eur J Pharmacol [Ixeris sonchifolia induced vasoconstriction effect and its mechanism in rat thoracic aorta] Authors: Lin YC, Hu SJ, Xu DL, Zheng GS Journal: Zhongguo Zhong Yao Za Zhi Primary aldosteronism, a major form of low renin hypertension: from screening to diagnosis. Authors: Giacchetti G, Mulatero P, Mantero F, Veglio F, Boscaro M, Fallo F Journal: Trends Endocrinol Metab Role and optimal dosing of angiotensin-converting enzyme inhibitors in heart failure. Authors: Kazi D, Deswal A Journal: Cardiol Clin Comparison of Nifedipine and Captopril in Children with Pulmonary Hypertension due to Broncopneumonia. Authors: Uner A, Dogan M, Demirtas M, Açikgöz M, Temel H, Kaya A, Caksen H Journal: J Trop Pediatr Great increase in antinociceptive potency of [Leu5]enkephalin after peptidase inhibition. Authors: Akahori K, Kosaka K, Jin XL, Arai Y, Yoshikawa M, Kobayashi H, Oka T Journal: J Pharmacol Sci Contractile effects of angiotensinogen and its multiple metabolization pathways on vessel walls. Authors: Cernucan DL, Gurzu B, Sl?tineanu S, Dumitriu IL, Sl?tineanu SM, Costuleanu M, Petrescu G Journal: Rev Med Chir Soc Med Nat Iasi Meconium increases type 1 angiotensin II receptor expression and alveolar cell death. Authors: Rosenfeld CR, Zagariya AM, Liu XT, Willis BC, Fluharty S, Vidyasagar D Journal: Pediatr Res Captopril reduces the severity of bowel damage in a neonatal rat model of necrotizing enterocolitis. Authors: Zani A, Eaton S, Leon FF, Malerba A, Hall NJ, De Coppi P, Smith VV, Pierro A Journal: J Pediatr Surg Effect of L-5-Hydroxytryptophan on drinking behavior in Coturnix japonica (Temminck and Schlegel, 1849) (Galliformes: Aves): involvement of renin-angiotensin system. Authors: Cedraz-Mercez PL, Almeida AC, Thomaz CM, Costa-e-Sousa RH, Olivares EL, Côrtes WS, Medeiros MA, Reis LC Journal: Braz J Biol Brain angiotensin-converting enzymes: role of angiotensin-converting enzyme 2 in processing angiotensin II in mice. Authors: Elased KM, Cunha TS, Marcondes FK, Morris M Journal: Exp Physiol Efficacy of pentoxifylline in the management of microalbuminuria in patients with diabetes. Authors: Rodríguez-Morán M, Guerrero-Romero F Journal: Curr Diabetes Rev Activation of a local renin angiotensin system in podocytes by glucose. Authors: Durvasula RV, Shankland SJ Journal: Am J Physiol Renal Physiol Method for comparing the structures of protein ligand-binding sites and application for predicting protein-drug interactions. Authors: Minai R, Matsuo Y, Onuki H, Hirota H Journal: Proteins Anticoagulant activity of captopril. Authors: Brecher AS, Murrey SJ, Gray KD, Poulimenos JN Journal: J Cardiovasc Pharmacol Noxious mechanical stimulation evokes the segmental release of opioid peptides that induce mu-opioid receptor internalization in the presence of peptidase inhibitors. Authors: Lao L, Song B, Chen W, Marvizón JC Journal: Brain Res Gender-specific regulation of pancreatic islet blood flow, insulin levels, and glycemia in spontaneously diabetic Goto-Kakizaki rats. Authors: Huang Z, Jansson L, Sjöholm A Journal: Clin Sci (Lond) Bilateral aldosterone-producing adenomas: differentiation from bilateral adrenal hyperplasia. Authors: Wu VC, Chueh SC, Chang HW, Lin WC, Liu KL, Li HY, Lin YH, Wu KD, Hsieh BS Journal: QJM Development of controlled release captopril granules coated with ethylcellulose and methylcellulose by fluid bed dryer. Authors: Stulzer HK, Silva MA, Fernandes D, Assreuy J Journal: Drug Deliv Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system. Authors: Corry DB, Eslami P, Yamamoto K, Nyby MD, Makino H, Tuck ML Journal: J Hypertens Attenuation of hepatic fibrosis through captopril and enalapril in the livers of bile duct ligated rats. Authors: Karimian G, Mohammadi-Karakani A, Sotoudeh M, Ghazi-Khansari M, Ghobadi G, Shakiba B Journal: Biomed Pharmacother Expression of angiotensin I-converting enzymes and bradykinin B2 receptors in mouse inner medullary-collecting duct cells. Authors: Redublo Quinto BM, Camargo de Andrade MC, Ronchi FA, Santos EL, Alves Correa SA, Shimuta SI, Pesquero JB, Mortara RA, Casarini DE Journal: Int Immunopharmacol Effect of yiqi huoxue recipe on cardiac function and ultrastructure in regression of pressure overload-induced myocardial hypertrophy in rats. Authors: Tong CQ, Di Y, Liu ZQ, Wang YH, He W, Dai EQ Journal: Chin J Integr Med Combination polypharmacy for cardiovascular disease prevention in men: a decision analysis and cost-effectiveness model. Authors: Newman J, Grobman WA, Greenland P Journal: Prev Cardiol Tissue distribution in mice of BPP 10c, a potent proline-rich anti-hypertensive peptide of Bothrops jararaca. Authors: Silva CA, Portaro FC, Fernandes BL, Ianzer DA, Guerreiro JR, Gomes CL, Konno K, Serrano SM, Nascimento N, Camargo AC Journal: Toxicon hPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3. Authors: Søndergaard HB, Brodin B, Nielsen CU Journal: Pflugers Arch Effects of angiotensin type 2 receptor overexpression in the rostral ventrolateral medulla on blood pressure and urine excretion in normal rats. Authors: Gao L, Wang W, Wang W, Li H, Sumners C, Zucker IH Journal: Hypertension Saireito probably prevents mesangial cell proliferation in HIGA mice via PDGF-BB tyrosine kinase inhibition. Authors: Hattori T, Sadakane C, Koseki J, Kase Y, Takeda S Journal: Clin Exp Nephrol Role of ACE/AT2R complex in the control of mesenteric resistance artery contraction induced by ACE/AT1R complex activation in response to Ang I. Authors: Su J, Palen DI, Boulares H, Matrougui K Journal: Mol Cell Biochem Renogram and deconvolution parameters in diagnosis of renal artery stenosis. Variants of background subtraction and analysis techniques. Authors: Kempi V Journal: Nuklearmedizin Amiodarone use after acute myocardial infarction complicated by heart failure and/or left ventricular dysfunction may be associated with excess mortality. Authors: Thomas KL, Al-Khatib SM, Lokhnygina Y, Solomon SD, Kober L, McMurray JJ, Califf RM, Velazquez EJ Journal: Am Heart J Plasma MMP-2, MMP-9 and N-BNP in long-term survivors following complicated myocardial infarction: relation to cardiac magnetic resonance imaging measures of left ventricular structure and function. Authors: Orn S, Manhenke C, Squire IB, Ng L, Anand I, Dickstein K Journal: J Card Fail Urocortin 2 combined with angiotensin-converting enzyme inhibition in experimental heart failure. Authors: Rademaker MT, Charles CJ, Nicholls MG, Richards AM Journal: Clin Sci (Lond) Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure. Authors: Jackson EK, Dubinion JH, Mi Z Journal: Clin Exp Pharmacol Physiol Antihypertensive efficacy of zofenopril compared with atenolol in patients with mild to moderate hypertension. Authors: Nilsson P Journal: Blood Press Suppl Blood pressure control and response rates with zofenopril compared with amlodipine in hypertensive patients. Authors: Farsang C Journal: Blood Press Suppl An evaluation of the initial and long-term antihypertensive efficacy of zofenopril compared with enalapril in mild to moderate hypertension. Authors: Mallion JM Journal: Blood Press Suppl Comparison of home and office blood pressure in hypertensive patients treated with zofenopril or losartan. Authors: Narkiewicz K Journal: Blood Press Suppl The evolution of ACE inhibition--a turning point in cardiovascular medicine. Authors: Hedner T, Narkiewicz K, Kjeldsen SE Journal: Blood Press Suppl In vivo regulation of AT1a receptor-mediated intracellular uptake of [125I]Val5-ANG II in the kidneys and adrenals of AT1a receptor-deficient mice. Authors: Li XC, Zhuo JL Journal: Am J Physiol Renal Physiol Balloon Angioplasty for Native Aortic Coarctation in Different Anatomic Variants. Authors: Massoud IE, Farghly HE, Abdul-Monem A, Botros N, Kassem A, Magraby AE, Dawood A, Abdul-Hakam M Journal: Pediatr Cardiol More fuel to the debate on the "epidemics of primary aldosteronism". Authors: Rossi GP, Pessina AC, Mantero F, Journal: Hypertension Properties of flaky affinity resin with co-continuous structure. Authors: Mori T, Tanaka A, Kubo T, Kaya K, Sakamoto M, Hosoya K Journal: Bioorg Med Chem Angiotensin converting enzyme inhibitor but not angiotensin receptor blockade or statin ameliorates murine adriamycin nephropathy. Authors: Tang SC, Leung JC, Chan LY, Eddy AA, Lai KN Journal: Kidney Int Regulation of gene expression in rats with heart failure treated with the thyroid hormone analog 3,5-diiodothyropropionic acid (DITPA) and the combination of DITPA and captopril. Authors: Maitra N, Adamson C, Greer K, Klewer S, Hoying J, Bahl JJ, Goldman S, Morkin E Journal: J Cardiovasc Pharmacol Antihypertensive efficacy of zofenopril plus hydrochlorothiazide fixed combination for treatment in metabolic syndrome. Authors: Malacco E, Omboni S Journal: Adv Ther Captopril to mitigate chronic renal failure after hematopoietic stem cell transplantation: a randomized controlled trial. Authors: Cohen EP, Irving AA, Drobyski WR, Klein JP, Passweg J, Talano JA, Juckett MB, Moulder JE Journal: Int J Radiat Oncol Biol Phys Effect of antecedent hypertension and follow-up blood pressure on outcomes after high-risk myocardial infarction. Authors: Thune JJ, Signorovitch J, Kober L, Velazquez EJ, McMurray JJ, Califf RM, Maggioni AP, Rouleau JL, Howlett J, Zelenkofske S, Pfeffer MA, Solomon SD Journal: Hypertension Hepatoprotective role of captopril on paraquat induced hepatotoxicity. Authors: Elmi A, Sadeghi Zh, Elmi S, Daraei B, Ghazi-Khansari M Journal: Hum Exp Toxicol Serotonergic receptor blockade in the lateral parabrachial nucleus: different effects on hypertonic and isotonic NaCl intake. Authors: David RB, Menani JV, De Luca LA Journal: Brain Res Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. Authors: Nauton L, Kahn R, Garau G, Hernandez JF, Dideberg O Journal: J Mol Biol [Comparative characteristic of angiotensin-converting enzyme inhibitor--captopril and the angiotensin II receptor blokers--losartan action on the oxidative metabolism in experimental hyperlipidemia in rabbits] Authors: Antelava NA, Gongadze NV, Gogolauri MI, Kezeli TD, Pachkoriia KZ Journal: Georgian Med News Parafac and PLS applied to determination of captopril in pharmaceutical preparation and biological fluids by ultraviolet spectrophotometry. Authors: Niazi A, Ghasemi N Journal: Ann Chim Valsartan in the treatment of heart failure or left ventricular dysfunction after myocardial infarction. Authors: Bissessor N, White H Journal: Vasc Health Risk Manag Captopril inhibits capillary degeneration in the early stages of diabetic retinopathy. Authors: Zhang JZ, Xi X, Gao L, Kern TS Journal: Curr Eye Res ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin. Authors: Wösten-van Asperen RM, Lutter R, Haitsma JJ, Merkus MP, van Woensel JB, van der Loos CM, Florquin S, Lachmann B, Bos AP Journal: Eur Respir J A patient with acute renal failure. Scleroderma crisis (SRC). Authors: de Vijlder HC, Ter Borg EJ Journal: Neth J Med [Malignant hypertension] Authors: Hamada M, Takahashi N, Sakamoto Y, Nishio I Journal: Nippon Rinsho [The prescription of drugs in a dental clinic of a Mexican university hospital] Authors: Gómez-Oliván LM, Márquez Rodríguez S, Pontigo Loyola P, Téllez López A, Amaya-Chávez A, Galar-Martínez M Journal: Farm Hosp Captopril and Lisinopril Decrease Acetaldehyde Effects upon the Prothrombin Time. Authors: Brecher AS, Dubord R Journal: Dig Dis Sci Role of the brain renin-angiotensin system in blood pressure regulation. Authors: Varoni MV, Palomba D, Demontis MP, Gianorso S, Pais GL, Anania V Journal: Vet Res Commun Effects of angiotensin II and captopril on rewarding properties of morphine. Authors: Hosseini M, Sharifi MR, Alaei H, Shafei MN, Karimooy HA Journal: Indian J Exp Biol Stents in the successful management of protein-losing enteropathy after fontan. Authors: Shahda S, Zahra M, Fiore A, Jureidini S Journal: J Invasive Cardiol A randomized double-blind placebo-controlled trial to increase feasibility of dobutamine stress echocardiography in patients with hypertension. Authors: Rodrigues AC, Hotta VT, Borges Neto FM, dos Santos JM, Trindade ML, Mathias W Journal: J Am Soc Echocardiogr Exploiting kinetic spectrophotometric determination of captopril, an angiotensin-converting enzyme inhibitor, in a multi-pumping flow system. Authors: Prior JA, Santos JL, Lima JL Journal: Anal Chim Acta

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