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anethole trithione Choleretic used to allay dry mouth and constipation due to tranquilizers.


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Additional comments :
(Anetholtrithion, Trithioanethol, Trithioparamethoxyphenylpropene)



Articles




PubmedHPLC determination of 4-hydroxy-anethole trithione in plasma via enzymatic hydrolysis and its application to bioequivalence study.
Authors:  Li W, Deng J, Qiao J, Li Q, Zhang Y
Journal: J Pharm Biomed Anal

PubmedNew sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity.
Authors:  Perrino E, Cappelletti G, Tazzari V, Giavini E, Del Soldato P, Sparatore A
Journal: Bioorg Med Chem Lett

PubmedDetermination of anethole trithione in human plasma using high performance liquid chromatography coupled with tandem mass spectrometric detection.
Authors:  Li T, Zhang Z, Jiao H, Zhang L, Tian Y, Chen Y, Pang X, Zhuang J
Journal: Anal Chim Acta

PubmedTissue specific increase of the catalytic subunits of the 26S proteasome by indirect antioxidant dithiolethione in mice: enhanced activity for degradation of abnormal protein.
Authors:  Kwak MK, Huang B, Chang H, Kim JA, Kensler TW
Journal: Life Sci

PubmedModulation of angiogenesis by dithiolethione-modified NSAIDs and valproic acid.
Authors:  Isenberg JS, Jia Y, Field L, Ridnour LA, Sparatore A, Del Soldato P, Sowers AL, Yeh GC, Moody TW, Wink DA, Ramchandran R, Roberts DD
Journal: Br J Pharmacol

PubmedHPLC determination of anethole trithione and its application to pharmacokinetics in rabbits.
Authors:  Jing Q, Shen Y, Ren F, Chen J, Jiang Z, Peng B, Leng Y, Dong J
Journal: J Pharm Biomed Anal

PubmedThe antioxidant anethole dithiolethione inhibits monoamine oxidase-B but not monoamine oxidase A activity in extracts of cultured astrocytes.
Authors:  Drukarch B, Flier J, Jongenelen CA, Andringa G, Schoffelmeer AN
Journal: J Neural Transm

Pubmed[A case of pneumatosis cystoides intestinalis developed in a patient with Sjogren syndrome during administration of anetholetrithion]
Authors:  Kato H, Nishi Y, Ohyama M, Tohyama T, Nakamura M
Journal: Nippon Shokakibyo Gakkai Zasshi

PubmedSeizures in the developing brain.
Authors:  Velísková J, Claudio OI, Galanopoulou AS, Lado FA, Ravizza T, Velísek L, Moshé SL
Journal: Epilepsia

Pubmed[Anethole dithiolethione: an antioxidant agent against tenotoxicity induced by fluoroquinolones]
Authors:  Pouzaud F, Christen MO, Warnet JM, Rat P
Journal: Pathol Biol (Paris)

Pubmed[Radiation protectants of the crystalline lens]
Authors:  Belkacémi Y, Pasquier D, Castelain B, Warnet JM, Lartigau E
Journal: Cancer Radiother

PubmedThe neuroprotective antioxidant alpha-lipoic acid induces detoxication enzymes in cultured astroglial cells.
Authors:  Flier J, Van Muiswinkel FL, Jongenelen CA, Drukarch B
Journal: Free Radic Res

PubmedA randomized phase IIb trial of anethole dithiolethione in smokers with bronchial dysplasia.
Authors:  Lam S, MacAulay C, Le Riche JC, Dyachkova Y, Coldman A, Guillaud M, Hawk E, Christen MO, Gazdar AF
Journal: J Natl Cancer Inst

PubmedUsefulness of basal and pilocarpine-stimulated salivary flow in primary Sjögren's syndrome. Correlation with clinical, immunological and histological features.
Authors:  Rosas J, Ramos-Casals M, Ena J, García-Carrasco M, Verdu J, Cervera R, Font J, Caballero O, Ingelmo M, Pascual E
Journal: Rheumatology (Oxford)

PubmedLens epithelial cell protection by aminothiol WR-1065 and anetholedithiolethione from ionizing radiation.
Authors:  Belkacémi Y, Rat P, Piel G, Christen MO, Touboul E, Warnet JM
Journal: Int J Cancer

PubmedEnhancement of salivary secretion and neuropeptide (substance P, alpha-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment.
Authors:  Nagano T, Takeyama M
Journal: J Pharm Pharmacol

PubmedAnethole dithiolethione regulates oxidant-induced tyrosine kinase activation in endothelial cells.
Authors:  Ben-Mahdi MH, Gozin A, Driss F, Andrieu V, Christen MO, Pasquier C
Journal: Antioxid Redox Signal

Pubmed[Severe hypernatremia secondary to gastric lavage]
Authors:  Mofredj A, Rakotondreantoanina JR, Farouj N
Journal: Ann Fr Anesth Reanim

PubmedAnetholtrithion stabilizes body weight fluctuation caused by excessive water drinking in a patient with schizophrenia: a case report.
Authors:  Matsuo S, Ninomiya H, Takasiba T, Sasaki Y
Journal: J Clin Psychiatry

PubmedTreatment of xerostomia with the bile secretion-stimulating drug anethole trithione: a clinical trial.
Authors:  Hamada T, Nakane T, Kimura T, Arisawa K, Yoneda K, Yamamoto T, Osaki T
Journal: Am J Med Sci

PubmedQuantitation of anethole dithiolthione using high performance liquid chromatography with electrochemical detection.
Authors:  Traber K, Packer L
Journal: Methods Enzymol

PubmedAnethole dithiolethione, a putative neuroprotectant, increases intracellular and extracellular glutathione levels during starvation of cultured astroglial cells.
Authors:  Dringen R, Hamprecht B, Drukarch B
Journal: Naunyn Schmiedebergs Arch Pharmacol

PubmedProtective effects of anethole dithiolethione against oxidative stress-induced cytotoxicity in human Jurkat T cells.
Authors:  Khanna S, Sen CK, Roy S, Christen MO, Packer L
Journal: Biochem Pharmacol

PubmedThe use of salivary stimulant pastilles to improve compliance in women taking oxybutinin hydrochloride for detrusor instability.
Authors:  Arango O
Journal: Br J Urol

PubmedChemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancer model.
Authors:  Lubet RA, Steele VE, Eto I, Juliana MM, Kelloff GJ, Grubbs CJ
Journal: Int J Cancer

PubmedAnethole dithiolethione prevents oxidative damage in glutathione-depleted astrocytes.
Authors:  Drukarch B, Schepens E, Stoof JC, Langeveld CH
Journal: Eur J Pharmacol

PubmedChemoprevention of colon cancer by dietary administration of naturally-occurring and related synthetic agents.
Authors:  Reddy BS
Journal: Adv Exp Med Biol

PubmedA comparative study of the effects of yohimbine and anetholtrithione on salivary secretion in depressed patients treated with psychotropic drugs.
Authors:  Bagheri H, Schmitt L, Berlan M, Montastruc JL
Journal: Eur J Clin Pharmacol

PubmedAssessment of the role of glutathione conjugation in the protection afforded by anethol dithiolthione against hexachloro-1,3-butadiene-induced nephrotoxicity.
Authors:  Bouthillier L, Charbonneau M, Brodeur J
Journal: Toxicol Appl Pharmacol

PubmedDetermination of noscapine, hexylresorcinol and anethole in cough lozenges by liquid chromatography.
Authors:  Lucangioli S, Fernández Otero G, Rodríguez V, Carducci CN
Journal: Boll Chim Farm

PubmedInhibition of NF-kappa B activation in human T-cell lines by anetholdithiolthione.
Authors:  Sen CK, Traber KE, Packer L
Journal: Biochem Biophys Res Commun

PubmedChemoprevention of colon cancer by minor dietary constituents and their synthetic analogues.
Authors:  Reddy BS
Journal: Prev Med

PubmedCold light fluorimetry: a microtitration technology for cell culture to evaluate anethole dithiolethione and other biothiols.
Authors:  Rat P, Christen MO, Thevenin M, Warnet JM, Adolphe M
Journal: Methods Enzymol

PubmedUse of linoleic acid radiolysis for assay of antioxidant action of anethole dithiolethione.
Authors:  Christen MO, Fackir L, Jore D
Journal: Methods Enzymol

PubmedAnethole dithiolethione: biochemical considerations.
Authors:  Christen MO
Journal: Methods Enzymol

PubmedChemoprevention of colon carcinogenesis by organosulfur compounds.
Authors:  Reddy BS, Rao CV, Rivenson A, Kelloff G
Journal: Cancer Res

PubmedPilocarpine and other cholinergic drugs in the management of salivary gland dysfunction.
Authors:  Ferguson MM
Journal: Oral Surg Oral Med Oral Pathol

PubmedEffects of chronic anethole trithione and amitriptyline treatment on rat parotid gland signalling.
Authors:  Glenert U
Journal: Eur J Pharmacol

PubmedEffect of anethole dithiolthione on human platelet aggregation.
Authors:  Selley ML, McGuiness JA, Bartlett MR, Ardlie NG
Journal: Arzneimittelforschung

PubmedAcute effects of a possible sialogogue, anethole trithione, in rat parotid glands.
Authors:  Glenert U
Journal: Eur J Pharmacol

PubmedAn unusual presentation of chronic graft-versus-host disease in an unrelated bone marrow transplantation.
Authors:  LeVeque FG
Journal: Oral Surg Oral Med Oral Pathol

PubmedSinglet oxygen-induced damage to rat lenses in vitro: protection by anisyldithiolthione.
Authors:  Tissie G, Latour E, Coquelet C, Bonne C
Journal: Adv Exp Med Biol

PubmedProtective effect of anethol dithiolthione against acetaminophen hepatotoxicity in mice.
Authors:  Warnet JM, Christen MO, Thevenin M, Biard D, Jacqueson A, Claude JR
Journal: Pharmacol Toxicol

PubmedEnhancement of phosphatidylinositol turnover and cyclic nucleotide accumulation by chronic anethole trithione treatment in rat submaxillary glands.
Authors:  Ukai Y, Taniguchi N, Yamazaki A, Kimura K
Journal: J Pharm Pharmacol

PubmedStudy of glutathione and glutathione related enzymes in acetaminophen-poisoned mice. Prevention by anethole trithione pretreatment.
Authors:  Warnet JM, Christen MO, Thevenin M, Biard D, Jacqueson A, Claude JR
Journal: Arch Toxicol Suppl

PubmedPharmacological studies on anethole trithione.
Authors:  Ukai Y, Shiraishi M, Takeshita K, Fukui T, Kura K, Kimura K
Journal: Arzneimittelforschung

PubmedEnhancement of salivary secretion by chronic anethole trithione treatment.
Authors:  Ukai Y, Taniguchi N, Takeshita K, Ogasawara T, Kimura K
Journal: Arch Int Pharmacodyn Ther

PubmedXerostomia due to Sjögren's syndrome. Diagnostic criteria, treatment and outlines for a continuous dental care programme and an open trial with Sulfarlem.
Authors:  Malmström MJ, Segerberg-Konttinen M, Tuominen TS, Hietanen JH, Wolf JE, Sane JI, Konttinen YT
Journal: Scand J Rheumatol

PubmedSynergistic effect of sialagogues in management of xerostomia after radiation therapy.
Authors:  Epstein JB, Schubert MM
Journal: Oral Surg Oral Med Oral Pathol

PubmedDithiolthione-induced alterations in hepatic glutathione and related enzymes in male mice.
Authors:  Davies MH, Blacker AM, Schnell RC
Journal: Biochem Pharmacol

PubmedSystemic therapy of salivary gland hypofunction.
Authors:  Fox PC
Journal: J Dent Res

PubmedEffects of oltipraz, BHA, ADT and cabbage on glutathione metabolism, DNA damage and lipid peroxidation in old mice.
Authors:  Stohs SJ, Lawson TA, Anderson L, Bueding E
Journal: Mech Ageing Dev

Pubmed[Protective effect of malotilate (diisopropyl 1,3-dithiol-2-ylidenemalonate) on chemical-induced hepatotoxicity]
Authors:  Nokata M, Katoh M, Inishi S, Sugimoto T
Journal: J Toxicol Sci

PubmedA new potent inhibitor of lipid peroxidation in vitro and in vivo, the hepatoprotective drug anisyldithiolthione.
Authors:  Mansuy D, Sassi A, Dansette PM, Plat M
Journal: Biochem Biophys Res Commun

PubmedTreatment of xerostomia in patients with primary Sjögren's syndrome with sulfarlem.
Authors:  Schiřdt M, Oxholm P, Jacobsen A
Journal: Scand J Rheumatol Suppl

PubmedEffects of anethole dithiolthione and 2(3)-tert-butyl-4-hydroxyanisole on schistosome granuloma formation.
Authors:  Feldman GM, Naples JM, Seed JL, Bueding E
Journal: Parasite Immunol

PubmedStudies on the whole-body distribution of 14C-trithioparamethoxyphenylpropene in mice.
Authors:  Isacsson G, Singer P
Journal: Scand J Dent Res

Pubmed[Lacrimal hyposecretion in patients under antidepressive treatment]
Authors:  Baserer T, Eker E, Oguz V, Akar S
Journal: Bull Soc Ophtalmol Fr

PubmedChronic anethole trithione treatment enhances the salivary secretion and increases the muscarinic acetylcholine receptors in the rat submaxillary gland.
Authors:  Ukai Y, Taniguchi N, Takeshita K, Kimura K, Enomoto H
Journal: Arch Int Pharmacodyn Ther

Pubmed[Clinical experience in the treatment of non-iatrogenic xerostomia and xerophthalmia with trithioparamethoxyphenylpropene]
Authors:  Bianucci G, Campana G, Maddali Bongi S, Castagnoli A, Passigli G
Journal: Clin Ter

PubmedChemoprotective effects of two dithiolthiones and of butylhydroxyanisole against carbon tetrachloride and acetaminophen toxicity.
Authors:  Ansher SS, Dolan P, Bueding E
Journal: Hepatology

PubmedEffect of Sialor in treatment of xerostomia in Sjögren's syndrome.
Authors:  Epstein JB, Decoteau WE, Wilkinson A
Journal: Oral Surg Oral Med Oral Pathol

PubmedIdentification and quantitation of a metabolite of anethol dithiolthione in rat and mouse urine using high-performance liquid chromatography.
Authors:  Masoud AN, Bueding E
Journal: J Chromatogr

Pubmed[Clinical picture, diagnosis and therapy of xerostomia--attempt of a survey under pathophysiological aspects (author's transl)]
Authors:  Chilla R
Journal: HNO

PubmedClinical trials of a sialogogue in humans: a preliminary report.
Authors:  Epstein JB
Journal: Spec Care Dentist

Pubmed[Interaction studies using catapresan depot perlongette and a sialogenous drug]
Authors:  Langbehn AF, Beurich HW, Kiebbel E, Wolk M
Journal: Med Welt

Pubmed[Clinical study with a sialagogue drug (sulfarlem S 25 = TTPT) in the treatment of xerostomia (author's transl)]
Authors:  Häusler R, Ritschard J
Journal: Schweiz Rundsch Med Prax

Pubmed[Hepatic tolerance of trithioparamethoxyphenylpropene in cirrhosis]
Authors:  Hecht Y
Journal: Med Chir Dig

Pubmed[Dry mouth and dry eyes (author's transl)]
Authors:  Rostan A
Journal: Schweiz Rundsch Med Prax

PubmedProsthetic management of Sjörgren's syndrome.
Authors:  Slabbert JC, Raubenheimer EJ
Journal: J Dent Assoc S Afr

PubmedContact allergy to toothpaste flavors.
Authors:  Andersen KE
Journal: Contact Dermatitis

Pubmed[Effect of SL 25 on radiogenic xerostomia in the radiotherapy of tumors in the region of neck and face (author's transl)]
Authors:  Hassenstein E, Müller R, Reinhard HJ
Journal: Strahlentherapie

Pubmed[Treatment of drug-induced dryness of the mouth]
Authors:  Durst W
Journal: Ther Ggw

Pubmed[Possible reparatory action of the syndrome of dry mouth by trithioparamethoxyphenylpropene]
Authors:  Hinojal Fonseca R, Lopez Arranz JS
Journal: Rev Esp Estomatol

Pubmed[Polarographic studies on pharmaceuticals. II. Polarography of anethole trithione]
Authors:  Sugii A, Kabasawa Y, Akamatsu T
Journal: Yakugaku Zasshi





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