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| aminorex |
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An amphetamine-like anorectic agent. It may cause pulmonary hypertension.
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Additional comments :
(Aminoxafen)
See Also: Muscimol, Pemoline
Articles
Pharmacokinetics and effects of aminorex in horses. Authors: Soma LR, Rudy JA, Uboh CE, Xu F, Snapp HM Journal: Am J Vet Res
Temporal trends and drug exposures in pulmonary hypertension: an American experience. Authors: Walker AM, Langleben D, Korelitz JJ, Rich S, Rubin LJ, Strom BL, Gonin R, Keast S, Badesch D, Barst RJ, Bourge RC, Channick R, Frost A, Gaine S, McGoon M, McLaughlin V, Murali S, Oudiz RJ, Robbins IM, Tapson V, Abenhaim L, Constantine G Journal: Am Heart J
Safety of drug therapies used for weight loss and treatment of obesity. Authors: Ioannides-Demos LL, Proietto J, Tonkin AM, McNeil JJ Journal: Drug Saf
A century of pulmonary hemodynamics. Authors: Fishman AP Journal: Am J Respir Crit Care Med
Primary pulmonary arterial hypertension: a look back. Authors: Fishman AP Journal: J Am Coll Cardiol
Noradrenergic modulation of ephedrine-induced hypophagia. Authors: Wellman PJ, Miller DK, Ho DH Journal: Synapse
Anorexigen-related cardiopulmonary toxicity. Authors: Gross SB, Lepor NE Journal: Rev Cardiovasc Med
Therapeutic and adverse actions of serotonin transporter substrates. Authors: Rothman RB, Baumann MH Journal: Pharmacol Ther
Appetite suppressants as agonist substitution therapies for stimulant dependence. Authors: Rothman RB, Blough BE, Baumann MH Journal: Ann N Y Acad Sci
[Pulmonary hypertension and obesity] Authors: Sztrymf B, Ioos V, Sitbon O, Parent F, Simonneau G, Humbert M Journal: Rev Pneumol Clin
Effects on serotonin in rat hypothalamus of D-fenfluramine, aminorex, phentermine and fluoxetine. Authors: Tao R, Fray A, Aspley S, Brammer R, Heal D, Auerbach S Journal: Eur J Pharmacol
Anorexigen-induced pulmonary hypertension and the serotonin (5-HT) hypothesis: lessons for the future in pathogenesis. Authors: Eddahibi S, Adnot S Journal: Respir Res
Risk factors for pulmonary arterial hypertension. Authors: Humbert M, Nunes H, Sitbon O, Parent F, Hervé P, Simonneau G Journal: Clin Chest Med
Effects of anorexinogen agents on cloned voltage-gated K(+) channel hKv1.5. Authors: Perchenet L, Hilfiger L, Mizrahi J, Clément-Chomienne O Journal: J Pharmacol Exp Ther
[Drug induced pulmonary hypertension] Authors: Sato N, Nakanishi N Journal: Nippon Rinsho
Anorectic drugs and pulmonary hypertension from the bedside to the bench. Authors: Michelakis ED, Weir EK Journal: Am J Med Sci
Recreational use of aminorex and pulmonary hypertension. Authors: Gaine SP, Rubin LJ, Kmetzo JJ, Palevsky HI, Traill TA Journal: Chest
Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Authors: Rothman RB, Baumann MH, Dersch CM, Romero DV, Rice KC, Carroll FI, Partilla JS Journal: Synapse
[Obesity: principles of drug therapy] Authors: Imoberdorf R, Ballmer PE Journal: Ther Umsch
[Development of pulmonary hypertension and multi-valvular damage caused by appetite depressants] Authors: Goldstein SE, Levy Y, Shoenfeld Y Journal: Harefuah
[Anorectics and pulmonary hypertension] Authors: Bíbová J, Hampl V Journal: Cas Lek Cesk
Appetite suppressants and cardiac valvulopathy. Current clinical perspectives. Authors: Gross SB Journal: Adv Nurse Pract
Delayed onset of pulmonary hypertension associated with an appetite suppressant, mazindol: a case report. Authors: Hagiwara M, Tsuchida A, Hyakkoku M, Nishizato K, Asai T, Nozawa Y, Tsuchihashi K, Shimamoto K Journal: Jpn Circ J
Aminorex to Fen/Phen: an epidemic foretold. Authors: Pollick C Journal: Circulation
Aminorex to Fen/Phen: an epidemic foretold. Authors: Tellier P Journal: Circulation
Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. Authors: Rothman RB, Ayestas MA, Dersch CM, Baumann MH Journal: Circulation
Complex vascular lesions at autopsy in a patient with phentermine-fenfluramine use and rapidly progressing pulmonary hypertension. Authors: Strother J, Fedullo P, Yi ES, Masliah E Journal: Arch Pathol Lab Med
Aminorex to fen/phen: an epidemic foretold. Authors: Fishman AP Journal: Circulation
Discriminative stimulus effects of S(-)-methcathinone (CAT): a potent stimulant drug of abuse. Authors: Young R, Glennon RA Journal: Psychopharmacology (Berl)
Monoclonal endothelial cells in appetite suppressant-associated pulmonary hypertension. Authors: Tuder RM, Radisavljevic Z, Shroyer KR, Polak JM, Voelkel NF Journal: Am J Respir Crit Care Med
Relearning the lessons of history: anorexigens and pulmonary hypertension. Authors: Langleben D Journal: Chest
Two different drug-induced pulmonary complications in a patient suffering from rheumatoid arthritis. Authors: Leeb BF, Scheinecker C, Schweitzer H, Smolen JS Journal: Br J Rheumatol
Aminorex, dexfenfluramine, and primary pulmonary hypertension. Authors: Kramer MS, Lane DA Journal: J Clin Epidemiol
The effect of anticoagulant therapy in primary and anorectic drug-induced pulmonary hypertension. Authors: Frank H, Mlczoch J, Huber K, Schuster E, Gurtner HP, Kneussl M Journal: Chest
Herbs, seeds, oil and eggs: a vasotoxic salad. Authors: Weber KT Journal: Cardiovasc Res
Appetite-suppressant drugs and primary pulmonary hypertension. Authors: Fishman AP Journal: N Engl J Med
The effects of aminorex and related compounds on brain monoamines and metabolites in CBA mice. Authors: Zheng Y, Russell B, Schmierer D, Laverty R Journal: J Pharm Pharmacol
Effects of chronic dexfenfluramine treatment on pulmonary hemodynamics in dogs. Authors: Naeije R, Maggiorini M, Delcroix M, Leeman M, Mélot C Journal: Am J Respir Crit Care Med
Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction. Authors: Weir EK, Reeve HL, Huang JM, Michelakis E, Nelson DP, Hampl V, Archer SL Journal: Circulation
[Iatrogenic pulmonary artery hypertension] Authors: Weitzenblum E, Kessler R, Chaouat A Journal: Rev Mal Respir
Metabolism of 4-methylaminorex ("EU4EA") in the rat. Authors: Henderson GL, Harkey MR, Chueh YT Journal: J Anal Toxicol
Stimulus properties of some analogues of 4-methylaminorex. Authors: Russell BR, Beresford RA, Schmierer DM, McNaughton N, Clark CR Journal: Pharmacol Biochem Behav
Pulmonary hypertension and dexfenfluramine. Authors: Cacoub P, Dorent R, Nataf P, Houppe JP, Piette JC, Godeau P, Gandjbakhch I Journal: Eur J Clin Pharmacol
Evaluation of the abuse liability of aminorex. Authors: Woolverton WL, Massey BW, Winger G, Patrick GA, Harris LS Journal: Drug Alcohol Depend
[Dietary pulmonary hypertension] Authors: Takagi K, Kondoh M Journal: Ryoikibetsu Shokogun Shirizu
[Primary pulmonary hypertension] Authors: Winkler J Journal: Z Gesamte Inn Med
[Aminorex-induced, plexogenic pulmonary arteriopathy: 25 years later!] Authors: Frank H, Gurtner HP, Kneussl M, Lang I, Mlczoch J Journal: Z Kardiol
Cocaine-stimulus generalization to two new designer drugs: methcathinone and 4-methylaminorex. Authors: Young R, Glennon RA Journal: Pharmacol Biochem Behav
Aminorex produces stimulus effects similar to amphetamine and unlike those of fenfluramine. Authors: Young R Journal: Pharmacol Biochem Behav
[Long-term follow-up of pulmonary hypertension of unknown etiology] Authors: Lang I, Kneussl M, Frank H, Mlczoch J Journal: Pneumologie
A fatality involving U4Euh, a cyclic derivative of phenylpropanolamine. Authors: Davis FT, Brewster ME Journal: J Forensic Sci
Specificity of pulmonary vascular lesions in primary pulmonary hypertension. A reappraisal. Authors: Pietra GG, Rüttner JR Journal: Respiration
[Prolonged survey of cases of pulmonary hypertension in relation to consumption of aminorex. Histological, quantitative and morphometric study of 9 cases] Authors: Widgren S Journal: Schweiz Med Wochenschr
Development of pulmonary aneurysm in primary pulmonary hypertension: a case report. Authors: Nienaber CA, Spielmann RP, Montz R, Bleifeld W, Mathey DG Journal: Angiology
Polymorphic debrisoquine and mephenytoin hydroxylation in patients with pulmonary hypertension of vascular origin after aminorex fumarate. Authors: Saner H, Gurtner HP, Preisig R, Küpfer A Journal: Eur J Clin Pharmacol
Primary pulmonary hypertension. An analysis of 28 cases and a review of the literature. Authors: Hughes JD, Rubin LJ Journal: Medicine (Baltimore)
[Chronic pulmonary hypertension of vascular etiology, plexogenic pulmonary arteriopathy and the appetite depressant Aminorex: lessons from an epidemic] Authors: Gurtner HP Journal: Schweiz Med Wochenschr
[Chronic pulmonary hypertension of vascular origin, plexogenic pulmonary arteriopathy and the appetite depressant aminorex: addenda to an epidemic] Authors: Gurtner HP Journal: Schweiz Med Wochenschr
Pulmonary hypertension associated with portal thrombosis. Authors: Flemale A, Sabot JP, Popijn M, Procureur M, Urbain G, Dierckx JP, Delmez JP Journal: Eur J Respir Dis
Long-term follow-up of pulmonary hypertension in patients with and without anorectic drug intake. Authors: Loogen F, Worth H, Schwan G, Goeckenjan G, Lösse B, Horstkotte D Journal: Cor Vasa
Aminorex and pulmonary hypertension. A review. Authors: Gurtner HP Journal: Cor Vasa
Thrombogenic effects of xenobiotics. Authors: Zbinden G, Grimm L Journal: Arch Toxicol Suppl
[Current status of plexogenic pulmonary arteriopathy of unknown origin] Authors: Lockhart A Journal: Bull Eur Physiopathol Respir
[Long-term course of primary vascular pulmonary hypertension with and without intake of appetite depressants] Authors: Voss H, Feigel H, Bücking J Journal: Z Kardiol
[A case of chronic pulmonary hypertension after fenfluramine intake] Authors: Gaul G, Blazek G, Deutsch E, Heeger H Journal: Wien Klin Wochenschr
[Modification of psychosocial adjustment by terminal disease] Authors: Heim E, Adler R, Moser A Journal: Z Psychosom Med Psychoanal
Primary pulmonary hypertension, a review. Authors: Widimský J Journal: Cor Vasa
[Severe adverse drug reactions among medical inpatients (author's transl)] Authors: Marty H, Winzenried P, Hess T, Lépine A, Stocker F, Hoigné R Journal: Schweiz Rundsch Med Prax
Primary pulmonary hypertension: follow-up of patients with and without anorectic drug intake. Authors: Mlczoch J, Probst P, Szeless S, Kaindl F Journal: Cor Vasa
Primary pulmonary hypertension. Authors: Fishman AP, Pietra GG Journal: Annu Rev Med
[Thrombocyte behavior in patients with "primary" pulmonary hypertension. Pathogenesis of aminorex-induced pulmonary hypertension] Authors: Mlczoch J Journal: Acta Med Austriaca Suppl
Pulmonary hypertension, "plexogenic pulmonary arteriopathy" and the appetite depressant drug aminorex: post or propter? Authors: Gurtner HP Journal: Bull Eur Physiopathol Respir
Long term effects of the anorectic agent fenfluramine alone and in combination with aminorex on pulmonary and systemic circulation in the pig. Authors: Mlczoch J, Weir EK, Reeves JT, Grover RF Journal: Basic Res Cardiol
Hemodynamic effects of long term feeding of sympathomimetic amines to swine. Authors: Orr JA, Ungerer T, Seavey E, Bisgard GE, Will JA Journal: J Environ Pathol Toxicol
[Course and prognosis of primary pulmonary hypertension] Authors: Turina J, Wirz P, Krayenbühl HP Journal: Schweiz Med Wochenschr
Pulmonary vascular disease. Authors: Heath D, Smith P Journal: Med Clin North Am
[Reversible pulmonary arterial hypertension after medication of aminorexfumarate (author's transl)] Authors: Simon H, Felix R Journal: Med Klin
Release of platelet 5-hydroxytryptamine by some anorexic and other sympathomimetics and their acetyl derivatives. Authors: Friström S, Airaksinen MM, Halmekoski J Journal: Acta Pharmacol Toxicol (Copenh)
[Effect of chronic hypoxic pulmonary hypertension on the effect of aminorex on the lesser circulation] Authors: Credner C Journal: Verh Dtsch Ges Inn Med
Pulmonary hypertension related to aminorex intake. Histologic, ultrastructural, and morphometric studies of 37 cases in Switzerland. Authors: Widgren S Journal: Curr Top Pathol
[Late diagnosis of a Menocil-induced pulmonary hypertension] Authors: Hansen B, Lüllmann H, Schaefer J Journal: Dtsch Med Wochenschr
[Drug-induced primary vascular pulmonary hypertension. Contribution to its etiology and clinical course] Authors: Schnabel KH, Schulz V, Busch S, Just H Journal: Med Welt
How study of geographic epidemiology of disease can help in detection of adverse drug reactions. Authors: Stolley PD Journal: Clin Pharmacol Ther
[Anorexic preparations and primary pulmonary hypertension] Authors: Ugriumova MO Journal: Ter Arkh
[On the mechanism of action of aminorexfumarate (author's transl)] Authors: Schuster J Journal: Arzneimittelforschung
[Two-year peroral administration of aminorex in the dog. 2] Authors: Stepanek J, Zak F Journal: Z Kardiol
[Two-year peroral administration of aminorex in the dog. 1] Authors: Stepanek J, Zak F Journal: Z Kardiol
Aminorex and pulmonary circulation. Authors: Seiler KU Journal: Arzneimittelforschung
Proceedings: Epidemiological remarks. Discussion. Authors: Epstein FH Journal: Pathol Microbiol (Basel)
Proceedings: The epidemic of primary pulmonary hypertension in Europe. Authors: Lüthy E Journal: Pathol Microbiol (Basel)
[Proceedings: Pulmonary arterial hypertension in patients treated with appetite depressants in Switzerland] Authors: Widgren S Journal: Verh Dtsch Ges Pathol
Aminorex and the pulmonary circulation of rats fed on a high fat diet. Authors: Smith P, Heath D Journal: Arzneimittelforschung
Effect of APMO on pulmonary and arterial blood pressure; a comparison with aminorex. Authors: Abdallah AH Journal: Eur J Pharmacol
[Evolution of primary vascular pulmonary hypertension following ingestion of aminorex fumarate (Menocil). Preliminary communication] Authors: Bass O, Gurtner HP Journal: Schweiz Med Wochenschr
[Pulmonary hypertension following chronic ingestion of aminorex in dogs. Preliminary communication] Authors: Stepanek J Journal: Schweiz Med Wochenschr
[Effect of chronic application of aminorex-fumarate on the pulmonary circulation of the rat] Authors: Engelhardt R, Kalbfleisch H Journal: Arzneimittelforschung
Pulmonary arterial pressure and structure in the patas monkey after prolonged administration of aminorex fumarate. Authors: Smith P, Heath D, Kay JM, Wright JS, McKendrick CS Journal: Cardiovasc Res
[Alteration of the acid-base equilibrium by the anorectic diphemethoxidine in comparison with the effect of amphetamine and aminorex] Authors: Stepanek J Journal: Arch Int Pharmacodyn Ther
[Apparently primary pulmonary arterial hypertension in a woman who had taken appetite depressants (Aminorex)] Authors: Berthou JD, Delahaye JP, Brune J, Dorsit G, Delaye J, Roques JC, Gonin A Journal: Rev Tuberc Pneumol (Paris)
[Changes in acid-base equilibrium caused by Aminorex and amphetamine in the dog] Authors: Stepanek J Journal: Schweiz Med Wochenschr
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