alphaprodine - Medical Dictionary

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alphaprodine		An opioid analgesic chemically related to and with an action resembling that of meperidine, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1067) [ Articles \| Books \| Images \| Discussion groups ]

Additional comments : (Prodine) Articles Structure determination of neoefrapeptins A to N: peptides with insecticidal activity produced by the fungus Geotrichum candidum. Authors: Fredenhagen A, Molleyres LP, Böhlendorf B, Laue G Journal: J Antibiot (Tokyo) Chiral resolution of 1,3-dimethyl-4-phenylpiperidine derivatives using high-performance liquid chromatography with a chiral stationary phase. Authors: Yin D, Khanolkar AD, Makriyannis A, Froimowitz M Journal: J Chromatogr A [Synthesis and CNS-activity of spirocyclic pethidine and prodine analogs] Authors: Wünsch B, Höfner G, Bauschke G Journal: Arch Pharm (Weinheim) Obstetrical medication and the newborn infant. II: The influence of meperidine (pethidine) on visual behaviour. Authors: Adams RJ Journal: Dev Med Child Neurol Sinusoidal fetal heart rate pattern during labor. Authors: Egley CC, Bowes WA, Wagner D Journal: Am J Perinatol Common stereospecificity of opioid and dopamine systems for N-butyrophenone prodine-like compounds. Authors: Iorio MA, Frigeni V, Bowman ER, Harris LS, May EL, Aceto MD Journal: J Med Chem GABAmimetics diminish antinociception of meperidine under conditions which enhance other opioid mu-agonists. Authors: Wynn RL, Bergman SA, Rudo FG, Leventer M Journal: Arch Int Pharmacodyn Ther Obstetrical medication and the human newborn: the influence of alphaprodine hydrochloride on visual behaviour. Authors: Adams RJ Journal: Dev Med Child Neurol The relationship between maternal labour analgesia and delay in the initiation of breastfeeding in healthy neonates in the early neonatal period. Authors: Matthews MK Journal: Midwifery A descriptive study of 201 uncombined alphaprodine HCl conscious sedations in pediatric dental patients (1982-1985). Authors: Lunt RC, Hward HE Journal: Pediatr Dent Measurement of alphaprodine by selected-ion monitoring. Authors: Kuhnert BR, Brashear WT, Syracuse CD Journal: J Chromatogr Nonlinear dose-response characteristics of alphaprodine sedation in preschool children. Authors: Lambert LA, Nazif MM, Moore PA, Zullo TG Journal: Pediatr Dent Local anesthesia and narcotic drug interaction in pediatric dentistry. Authors: Moore PA Journal: Anesth Prog Supraventricular tachycardia associated with postpartum metoclopramide administration. Authors: Bevacqua BK Journal: Anesthesiology Narcotic sedation: an evaluation of cardiopulmonary parameters and behavior modification in pediatric dental patients. Authors: Currie WR, Biery KA, Campbell RL, Mourino AP Journal: J Pedod Conscious sedation for minor gynecologic surgery in the ambulatory patient. A pilot study. Authors: Shane SM, Speedie LJ, Rao L, Niedermeyer E, McPherson R Journal: Anesth Prog Combined analgesic/neuroleptic activity in N-butyrophenone prodine-like compounds. Authors: Iorio MA, Reymer TP, Frigeni V Journal: J Med Chem Effects of variable alphaprodine dose levels on arterial blood gases in rhesus monkeys. Authors: Gross R, Nazif MM, Zullo T Journal: Anesth Prog Respiratory arrest and prolonged respiratory depression after one low, subcutaneous dose of alphaprodine for obstetric analgesia. A case report. Authors: Fuller JD, Crombleholme WR Journal: J Reprod Med Sinusoidal fetal heart rate. Authors: De Muylder X Journal: J Perinat Med Synthetic analgesics and other phenylpiperidines: effects on uptake and storage of dopamine and other monoamines mouse forebrain tissue. Authors: Baldessarini RJ, Kula NS, Francoeur D, Finklestein SP, Murphy F, Neumeyer JL Journal: Life Sci Drugs that wouldn't die. Authors: Weintraub M, Northington FK Journal: JAMA Neonatal responses to alphaprodine administered during labor. Authors: Murakawa K, Abboud TK, Yanagi T Journal: Anesth Analg Lack of depletion of striatal dopamine by phenylpiperidine analgesics. Authors: Baldessarini RJ, Neumeyer JL Journal: N Engl J Med Cyanosis of the hands following the use of alphaprodine in dental anaesthesia. Authors: Fuller HD Journal: Can Anaesth Soc J Racemic and optically active 1,3,3-trimethyl-4-phenyl-4-(propionyloxy)piperidine. Authors: Ahmed FR, Laws GF, Madani AE, Casy AF Journal: J Med Chem Evaluation of an alphaprodine-hydroxyzine combination as a sedative agent in the treatment of the pediatric dental patient. Authors: Doring KR Journal: J Am Dent Assoc Risk appraisal of narcotic sedation for children. Authors: Moore PA, Goodson JM Journal: Anesth Prog Alphaprodine hydrochloride for obstetrics. Authors: Rimar JM Journal: MCN Am J Matern Child Nurs Nisentil-induced respiratory arrest: report of case. Authors: Finder RL, Schwartz PJ, Bennett CR Journal: ASDC J Dent Child Opioid analgesics in anesthesia: with special reference to their use in cardiovascular anesthesia. Authors: Bovill JG, Sebel PS, Stanley TH Journal: Anesthesiology Problems of medication with the pediatric patient. Authors: Brandt SK, Bugg JL Journal: Dent Clin North Am Sinusoidal fetal heart rate. Ominous or benign? Authors: Theard FC, Penney LL, Otterson WN Journal: J Reprod Med Sinusoidal rhythm caused by fetal hemorrhage during fetoscopy. Authors: Nicolini U, Hertogs K, Rodeck CH Journal: J Perinat Med Rebreathing and end-tidal CO2 during spontaneous breathing with the Bain circuit. Authors: Spoerel WE Journal: Can Anaesth Soc J Maternal and fetal response to alphaprodine during labor. A preliminary study. Authors: Miller FC, Mueller E, McCart D Journal: J Reprod Med The clinical significance of a sinusoidal fetal heart rate pattern associated with alphaprodine administration. Authors: Veren D, Boehm FH, Killam AP Journal: J Reprod Med Regional obstetric anesthesia and newborn behavior: a reanalysis toward synergistic effects. Authors: Lester BM, Als H, Brazelton TB Journal: Child Dev Neonatal neurobehavioral effects of inhalation analgesia for vaginal delivery. Authors: Stefani SJ, Hughes SC, Schnider SM, Levinson G, Abboud TK, Henriksen EH, Williams V, Johnson J Journal: Anesthesiology Sinusoidal fetal heart rate pattern: its definition and clinical significance. Authors: Modanlou HD, Freeman RK Journal: Am J Obstet Gynecol Anesthetic misadventures. Authors: Journal: J Am Dent Assoc Hypoxic encephalopathy after the administration of alphaprodine hydrochloride. Authors: Okuji DM Journal: J Am Dent Assoc Muscle rigidity and respiratory arrest with alphaprodine: a case report. Authors: DePaola LG, Eisen MZ Journal: J Baltimore Coll Dent Surg Effects of tetrabenazine and phenylpiperidine analgesics during daily clorgyline treatment. Authors: Leander JD Journal: Psychopharmacology (Berl) Electronic study of receptor binding of analgesic aryl moiety II: Prodine analogs. Authors: Razzak KS, Hamid KA Journal: J Pharm Sci Sinusoidal fetal heart rate pattern in association with amnionitis. Authors: Gleicher N, Runowicz CD, Brown BL Journal: Obstet Gynecol Comparison of haemodynamic effects of anaesthetic doses of alphaprodine and sulfentanil in the dog. Authors: Reddy P, Liu WS, Port D, Gillmor S, Stanley TH Journal: Can Anaesth Soc J Comparison of morphine, meperidine, anileridine, and alphaprodine on schedule-controlled responding and analgesia. Authors: Leander JD Journal: Pharmacol Biochem Behav A comparison of alphaprodine and meperidine pharmacokinetics. Authors: Fung DL, Asling JH, Eisele JH, Martucci R Journal: J Clin Pharmacol A submucous technique utilizing a narcotic and a potentiator. Authors: Metroka DC, Marchesani JR, Carrel R Journal: J Pedod Investigation of narcotics and antitussives using drug discrimination techniques. Authors: Overton DA, Batta SK Journal: J Pharmacol Exp Ther Sedation of the autistic patient for dental procedures. Authors: Braff MH, Nealon L Journal: ASDC J Dent Child Carbon dioxide laser surgery of larynx. Anesthetic technique. Authors: Oliverio RM, Fermon CM Journal: N Y State J Med Attenuating the rate-decreasing effects of phenylpiperidine analgesics by pentobarbital. Authors: Leander JD Journal: Psychopharmacology (Berl) Relative potencies and durations of action with respect to respiratory depression of intravenous meperidine, fentanyl and alphaprodine in man. Authors: Kaufman RD, Aqleh KA, Bellville JW Journal: J Pharmacol Exp Ther Sinusoidal fetal heart rate pattern associated with alphaprodine administration. Authors: Gray JH, Cudmore DW, Luther ER, Martin TR, Gardner AJ Journal: Obstet Gynecol Comparing the effects of anileridine, alphaprodine and fentanyl on schedule-controlled responding by pigeons. Authors: Leander JD Journal: J Pharmacol Exp Ther Renal blood flow: differences in autoregulation during anesthesia with halothane, methoxyflurane, or alphaprodine in the dog. Authors: Leighton KM, Macleod BA, Bruce C Journal: Anesth Analg Electric shock titration: effects of meperidine, anileridine and alphaprodine. Authors: Dykstra LA, Leander JD Journal: Pharmacol Biochem Behav Three-dimensional molecular illustrations II: Isoelectrostatic energy contour spheres of influence applied to narcotic molecules. Authors: Breon TL, Petersen H, Paruta AN Journal: J Pharm Sci Preanesthetic and intrapartal medications. Authors: McDonald JS Journal: Clin Obstet Gynecol The blockade of serotonin uptake into synaptosomes:relationship to an interaction with monoamine oxidase inhibitors. Authors: Sinclair JG, Lo GF Journal: Can J Physiol Pharmacol Relationships between opiate receptor binding and analgetic properties of prodine-type compounds. Authors: Klee WA, Iorio MA Journal: J Med Chem The effect of drugs on uterine activity. Authors: Petrie RH, Wu R, Miller FC, Sacks DA, Sugarman R, Paul RH, Hon EH Journal: Obstet Gynecol 2-Azabicyclo (2.2.2)octane analogues of the prodine analgetics. Authors: Clark CR, Holbrook JM, Borne RF Journal: J Med Chem Dobutamine and general anaesthesia: a study of the response of arterial pressure, heart rate and renal blood flow. Authors: Leighton KM, Bruce C Journal: Can Anaesth Soc J Carbon dioxide output in anaesthesia. Authors: Bain JA, Spoerel WE Journal: Can Anaesth Soc J Stereochemical studies on medicinal agents. 19. X-ray crystal structures of two (+/-)-allylprodine diastereomers. The role of the allyl group in conferring high stereoselectivity and potency at analgetic receptors. Authors: Portoghese PS, Shefter E Journal: J Med Chem A study of anaesthesia depth by power spectral analysis of the electroencephalogram (EEG). Authors: Berezowskyj JL, McEwen JA, Anderson GB, Jenkins LC Journal: Can Anaesth Soc J Ketamine-pancuronium-narcotic technic for cardiovascular surgery in infants--a comparative study. Authors: Levin RM, Seleny FL, Streczyn MV Journal: Anesth Analg Quantum chemical studies of meperidine and prodine. Authors: Loew GH, Jester JR Journal: J Med Chem A study of three preoperative sedative combinations. Authors: Tobias M, Lipschultz DH, Album MM Journal: ASDC J Dent Child Radioimmunoassay for anileridine, meperidine and other N-substituted phenylpiperidine carboxylic acid esters. Authors: Van Vunakis H, Freeman DS, Gjika HB Journal: Res Commun Chem Pathol Pharmacol Production and characterization of antibodies to meperidine. Authors: Catlin DH, Schaeffer JC, Fischer JF Journal: Res Commun Chem Pathol Pharmacol Obstetric anesthesia as a neonatal risk factor in normal labor and delivery. Authors: Scanlon JW Journal: Clin Perinatol Nisentil as an adjunct in dental anesthesia. Authors: Wallace LN Journal: Anesth Prog Anesthesia for laparoscopy. Authors: Keith L, Silver A, Becker M Journal: J Reprod Med Intravenous amnesia--an appraisal after seven years and 10,500 administrations. Authors: Shane SM, Carrel R, Vandenberge J Journal: Anesth Prog Pancuronium and renal perfusion: a comparison of neuromuscular blocking agents. Authors: Leighton KM, Koth B, Bruce C Journal: Can Anaesth Soc J Neurobehavioral responses of newborn infants after maternal epidural anesthesia. Authors: Scanlon JW, Brown WU, Weiss JB, Alper MH Journal: Anesthesiology Anaesthesia for cervical osteotomy. Authors: Chang J Journal: Can Anaesth Soc J Interactions of some analgesics and antidepressants with phenelzine or reserpine in the mouse. Authors: Ahtee L, Jounela AJ, Saarnivaara L, Simola I Journal: Pharmacology Analgesia during labor: effect on the fetus and neonate. Authors: Clark RB Journal: Clin Anesth Analgesic "cocktails" for pneumoencephalography: ketamine, diazepam, alphaprodine, and droperidol. Authors: Wolfson B, Kielar CM, Shenoy NR, Hetrick WD Journal: Anesth Analg The anaesthetic management of pelvic laparoscopy. Authors: Calverley RK, Jenkins LC Journal: Can Anaesth Soc J The effect of narcotic analgesics on the uptake of 5-hydroxytryptamine and (-)-metaraminol by blood platelets. Authors: Ahtee L, Saarnivaara L Journal: Br J Pharmacol Stereochemical studies on medicinal agents. 14. Relative stereochemistries and analgetic potencies of diastereomeric 3-allyl and 3-propyl derivatives of 1-methyl-4-phenyl-4-propionoxypiperidine. Authors: Bell KH, Portoghese PS Journal: J Med Chem Stereochemical studies on medicinal agents. 13. Correlation of the solid-state conformations of 1,3,5-trimethyl- and 1,3-dimethyl-4-phenyl-4-propionoxypiperidine enantiomers with their absolute stereoselectivity at analgetic receptors. Authors: Portoghese PS, Gomaa ZS, Larson DL Journal: J Med Chem Stereochemical studies on medicinal agents. 12. The distinction of enantiotopic groups in the interaction of 1-methyl-4-phenyl-4-propionoxypiperidine with analgetic receptors. Authors: Larson DL, Portoghese PS Journal: J Med Chem Neuroleptanesthesia for general surgery. Authors: Foldes FF Journal: Int Anesthesiol Clin Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine. Authors: Gorodetzky CW Journal: Toxicol Appl Pharmacol Ethoheptazine-monoamine oxidase inhibitor interaction in rabbits. Authors: Sinclair JG Journal: Can J Physiol Pharmacol A clinical study of a modified intravenous amnesia technique for pedodontia patients. Authors: Carrel R Journal: Bull Phila Cty Dent Soc Pharmacokinetics, metabolism, and urinary excretion of ( 3 H)alphaprodine in dogs. Authors: Abdel-Monem MM, Harris PA, Portoghese PS Journal: J Med Chem Stereochemical studies on medicinal agents. 11. Metabolism and distribution of prodine isomers in mice. Authors: Abdel-Monem MM, Larson DL, Kupferberg HJ, Portoghese PS Journal: J Med Chem Postpartum tubal ligation under local anesthesia. Authors: Munson AK, Scott JR Journal: Obstet Gynecol Fatality after use of alphaprodine in analgesia for dental surgery: report of case. Authors: Hine CH, Pasi A Journal: J Am Dent Assoc Methodological problems in conditioning the headturning response of newborn infants. Authors: Clifton RK, Meyers WJ, Solomons G Journal: J Exp Child Psychol Inhibition of constriction-induced reactive hyperemic edema. Authors: Brown JH, Garrett RL Journal: Proc Soc Exp Biol Med Fatality following use of alphaprodine. Authors: Hine CH, Pasi A Journal: Clin Toxicol

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